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🐾 Stay ahead of fleas—because your cat deserves the best defense!
Advantage II Large Cat is a vet-recommended topical flea treatment designed for cats over 9 lbs and 8 weeks old. It kills adult fleas, larvae, and eggs within 12 hours and provides 30 days of waterproof, fragrance-free protection. Easy to apply with no prescription required, it effectively breaks the flea life cycle to prevent infestations and keep your cat comfortable and healthy.














| ASIN | B004QN0MJQ |
| Active Ingredients | Imidacloprid, Pyriproxyfen |
| Age Range Description | 8 weeks and older |
| Allergen Information | Allergen-Free |
| Brand | Advantage |
| Brand Name | Advantage |
| Customer Reviews | 4.5 out of 5 stars 14,753 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089202246 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Volume | 3.2 ml |
| Item Weight | 22.68 g |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 81520224 |
| Model Number | 86336790 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Cat |
| UPC | 727516696311 724089378774 643996929094 724089616852 724089202246 024089616853 788995790068 891962001323 |
| Unit Count | 4 Count |
| Volume | 3.2 ml |
D**N
Works fast and keeps the fleas away!
I use Advantage II Large Cat (for cats over 9 lbs) on my big boy and it’s been excellent. Within about 12 hours of applying it I started seeing dead fleas, and after a full application the problem was under control. It kills adults, larvae, and eggs, so it actually breaks the cycle instead of just treating what’s visible. Application is easy just part the fur at the base of the neck and apply. No strong smell, and once it’s dry it’s waterproof. He’s over 9 lbs so this size is perfect for him, and I’ve had no irritation or issues. Reliable, vet-recommended, and effective. Highly recommend for large cats if you’re dealing with fleas or want solid monthly prevention!
J**A
It worked very well for my cats!
I have two indoor cats that had never had fleas before. After a trip, we noticed they were scratching a lot. I wasn’t sure the first product had completely solved the problem, so I tried Advantage II. I applied it to both cats on the same day. The next day, I found several fleas around the house, especially near their favorite sleeping area. The fleas were large, but they were lying on their sides and barely moving, which showed the product was working. My cats were much more comfortable after the treatment, and the number of fleas quickly started to decrease. I’ll continue vacuuming to help break the flea cycle, but I’m very happy with the results so far. It was easy to apply and seemed to work quickly. I recommend it to anyone dealing with a similar situation, especially since sometimes you don’t see fleas on your pets — you only notice the scratching.
B**E
Fast acting, easy application.
Worked well. I have a long haired and short haired cat and had no problems with apply on either of them. I noticed dead fleas by the morning and any scratching and stopped. Great product and highly recommend.
R**N
Good value
Good value
K**Y
Killed my cat’s flea infestation.
My cat recently had a flea infestation. His normal collar was not working, and this product came highly recommended from my sister who has five cats as well. It was very effective in combating his fleas. They were gone within a week. It seems to last as long as it says it does. My sister typically retreats after three weeks for her babies. I am currently on second dose and we have yet to have any fleas. Overall, I am very pleased with this product. It does not leave a scent that I noticed my cat did not have skin irritation or hair loss.
P**D
Advantage II for large cats
I was very skeptical this would work but I needed to try something that promised to treat large cats. I have very large cat that weighs in at 18 lbs of muscle, teeth, and claws, that gives you only 1 chance to treat her. After 24 hours nothing but dead fleas were left. 3 weeks later still no fleas or eggs. Thank you Advantage for produ ing a product that works!
H**T
Works well for my cats
My cats have benefited from Advantage II over the years. I remember Advantage used to be precription only; I'm not sure if this is a milder OTC version. We don't always have the luxury of prescription flea treatments. I usually give my cats a bath first and wait until they are dry and then put this on the back of their neck. This version of Advantage is affordable enough for me. In the Summer, I really need to give them Bath+Advantage once a month where I live. Grooming and trimming a long hair first, then Bath, then Advantage worked best for my long hair big boy cat.
C**.
Easy to place
Unfortunately this year fleas are horrible. Not saying this product did not work, but didn’t work long term for us. It was easy to apply. Don’t take my word for it because I’m in Oklahoma and our winter was not cold enough to eliminate the fleas
Trustpilot
1 month ago
3 weeks ago