--- product_id: 79504882 title: "ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP" brand: "isispharma" price: "¥15091" currency: JPY in_stock: true category: "Isis Pharma" url: https://www.desertcart.jp/products/79504882-isis-pharma-neotone-depigmenting-serum-anti-pigmentation-anti-dark-spot store_origin: JP region: Japan --- # Made in USA, trusted worldwide Lightweight 30ml serum drop Clinically proven formula ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP **Brand:** isispharma **Price:** ¥15091 **Availability:** ✅ In Stock ## Summary > ✨ Glow Beyond Limits – Because Your Skin Deserves the Spotlight ✨ ## Quick Answers - **What is this?** ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP by isispharma - **How much does it cost?** ¥15091 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/79504882-isis-pharma-neotone-depigmenting-serum-anti-pigmentation-anti-dark-spot) ## Best For - isispharma enthusiasts ## Why This Product - Trusted isispharma brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Compact & Travel-Friendly:** 30ml dropper bottle fits perfectly in your professional on-the-go skincare arsenal. - • **Lightweight Serum Texture:** Absorbs quickly without residue, perfect for daily use under makeup or alone. - • **Targeted Dark Spot Correction:** Clinically designed to visibly reduce pigmentation and dark spots for a flawless complexion. - • **Trusted Brand with Proven Results:** Backed by a 4.4-star rating from 746 users, ensuring reliability and satisfaction. - • **Universal Skin Tone Compatibility:** Formulated specifically for deep skin tones, enhancing natural radiance and evenness. ## Overview ISIS PHARMA Neotone Depigmenting Serum is a clinically formulated 30ml treatment designed to reduce dark spots and pigmentation, especially effective for deep skin tones. Made in the USA and highly rated by users, this lightweight serum absorbs quickly, making it ideal for daily use and professional lifestyles seeking radiant, even skin. ## Description ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML Good For You ## Features - Isis Pharma Neotone Pigmentation Spots - Serum ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00CI2KP9O | | ASIN | B00CI2KP9O | | Brand | IsisPharma | | Country of Origin | USA | | Country of Origin | USA | | Customer Reviews | 4.4 4.4 out of 5 stars (746) | | Date First Available | 25 January 2016 | | Generic Name | serum | | Is Discontinued By Manufacturer | No | | Item Dimensions LxWxH | 12 x 5.2 x 3.2 Centimeters | | Item Form | Drop | | Item Type Name | serum | | Item Volume | 30 Millilitres | | Item Weight | 0.03 Kilograms | | Item Weight | 32 g | | Item model number | SG_B00CI2KP9O_US | | Manufacturer | ISIS PHARMA | | Manufacturer | ISIS PHARMA | | Manufacturer Part Number | 0477834 | | Model Number | SG_B00CI2KP9O_US | | Number of Items | 1 | | Product Benefits | Anti Dark,Dark | | Product Dimensions | 11.99 x 5.21 x 3.2 cm; 32 g | | Skin Tone | Deep | | Skin Type | Normal | | UPC | 639382121180 784190477834 792486553827 | ## Product Details - **Brand:** IsisPharma - **Item Form:** Drop - **Item Volume:** 30 Millilitres - **Item Weight:** 0.03 Kilograms - **Number of Items:** 1 - **Product Benefits:** Anti Dark,Dark - **Skin Type:** Normal - **UPC:** 639382121180 784190477834 792486553827 ## Images ![ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP - Image 1](https://m.media-amazon.com/images/I/41qxEWINHPL.jpg) ![ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP - Image 2](https://m.media-amazon.com/images/I/216gAnSFXDL.jpg) ![ISIS PHARMA NEOTONE DEPIGMENTING SERUM ANTI PIGMENTATION ANTI DARK SPOT 25ML SHIP WORLDWIDE BY CIRCLE SHOP - Image 3](https://m.media-amazon.com/images/I/61EiBUdB2SL.jpg) ## Questions & Answers **Q: Is that work for dark circles?** A: Hi its treat dark-spot not sure if treat Circels . you visit ISIS pharma company website .there Doctors assigned to give you free consultation online **Q: CHow to use Neotone serum? Can i apply it on the whole face? or only the hyperpigmented areas?thanks.** A: I only use on the hyperpigmented area. **Q: is this good for bikini line darkest and armpits?** A: not for for bikini line darkest and armpits use On your face, neckline, and hands Use Neotone Serum every night on darks spots visible . During the treatment period, use suitable sun protection : Neotone Radiance SPF 50+ or a product from the Uveblock range with SPF 50+ on areas exposed to the sun. **Q: What are the Ingredients?** A: Thanks to its combined formula of 6 synergic active ingredients, NEOTONE stops the overproduction of melanin and eliminates efficiently the pigmentation spots already present in the skin: 1. Glycolic Acid exfoliates gently the preformed melanin from the skin’s surface. It clears the skin exfoliating dead cells 2. Ascorbic Acid enhances skin radiance. Its reveals and renews a luminous skin 3. Salicylic Acid exfoliates through the reduction of corneocyte 4. Alpha-Arbutin which inhibits melanogenesis through tyrosinase inhibition 5. Lumiskin (Diacetyl Boldine) inhibits tyrosinase activity 6. Licorice Extract acts on melanin overproduction and tyrosinase inhibition ## Frequently Bought Together - Isis Pharma Neotone Pigmentation Spots - Serum - Isis Pharma Neotone Prevent SPF 50+, 30ml - ISISPharma NEOTONE LIGHTENING EYE CONTOUR CARE Cream - Gel 15 ml --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.jp/products/79504882-isis-pharma-neotone-depigmenting-serum-anti-pigmentation-anti-dark-spot](https://www.desertcart.jp/products/79504882-isis-pharma-neotone-depigmenting-serum-anti-pigmentation-anti-dark-spot) --- *Product available on Desertcart Japan* *Store origin: JP* *Last updated: 2026-10-20*