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💧 See the difference, feel the comfort — hydration that keeps up with your busy life!
Systane Hydration Lubricating & Hydrating Eye Drops deliver long-lasting moisture with a preservative-free formula combining HP-Guar and Hyaluronic Acid. Packaged in convenient single-use vials, these drops provide sterile, on-the-go relief for dry, irritated eyes, including those sensitive to preservatives and contact lens wearers. Trusted by eye care professionals, they are ideal for managing dryness caused by environmental stress and extended screen exposure.




| ASIN | B0857XD9V6 |
| Active Ingredients | Polyethylene glycol 400, propylene glycol |
| Additional Features | Long-Lasting |
| Age Range Description | All |
| Best Sellers Rank | #3,671 in Health & Household ( See Top 100 in Health & Household ) #25 in Moisturizing Eye Drops #86 in Vision Products |
| Brand | Systane |
| Brand Name | Systane |
| Container Type | Vial |
| Customer Reviews | 4.8 out of 5 stars 6,477 Reviews |
| Dosage Form | Drops |
| Global Trade Identification Number | 00300651437041 |
| Item Dimensions | 2.95 x 1.38 x 4.65 inches |
| Item Form | Drop |
| Item Highlight | Combines HP-Guar & Hyaluronic Acid, Multi-Dose Eye Drops for Irritation & Dryness, Moisturizing & Soothing |
| Item Weight | 2.72 ounces |
| Item dimensions L x W x H | 2.95 x 1.38 x 4.65 inches |
| Manufacturer | AmazonUs/ALFQ7 |
| Manufacturer Part Number | 0065143704 |
| Model Number | 0065143704 |
| Number of Items | 1 |
| Package Type Name | R |
| Product Benefits | Hydration |
| Specific Uses For Product | Dry Eye |
| Target Use Body Part | Eyes |
| UPC | 300651437041 |
M**S
The best eye drops I’ve found for wearing contacts
I’ve worn contacts for years and have always struggled with very dry eyes. My eye doctor recommended these to me, and they have been my favorite eye drops ever since. I used to feel like I was reaching for eye drops throughout the entire day, but with these I personally only need them about once during the day and sometimes again at night. They keep my eyes feeling hydrated and make wearing my contacts much more comfortable throughout the day. I also really like the individual vials—they’re convenient to keep with me and easy to use. After trying so many different eye drops over the years, these are the ones I continue to come back to.
T**N
My judgement is affirmed.
I use these drops every day. My recomendation is not based on a week of experimentation or the excitement of opening a new package. It is based on long-term, repeated use under ordinary, everyday conditions. I have sampled a long line of competitors, some promising miracle relief, others carrying prescription labels that implied greater authority. Yet when the evidence was weighed—not marketing claims, but actual results—this product consistently prevailed. I place particular weight on the preservative-free formulation. For anyone using lubricating drops multiple times throughout the day, preservatives are not an insignificant consideration. Eliminating them is more than a marketing bullet point; for many users with sensitive eyes, it is an important advantage. I personally use only the single-use vials. While the multi-dose bottle contains the same formulation, I prefer the simplicity and reassurance of opening a fresh vial each time. An unusual fact in the record deserves mention. Although the manufacturer recommends storing the product at room temperature, I keep my vials refrigerated. That is simply my personal preference. The cool drops are especially soothing to me. I offer that observation not as medical advice or as a recommendation that others depart from the manufacturer's instructions, but merely as one user's experience. I also want to emphasize an important limitation. Dry eye is not a single condition with a single solution. Some people may need occasional lubrication; others may require more frequent use. The appropriate frequency depends on the individual's circumstances and should follow the product's directions. More importantly, I strongly advise every prospective user to read every warning and precaution on the package. If you experience significant eye pain, vision changes, persistent redness, worsening symptoms, or anything beyond ordinary dry eye, this matter belongs in the hands of a qualified eye-care professional—not an Amazon review. There are many excellent lubricating eye drops on the market, and what works beautifully for one person may not work as well for another. Dry eye is remarkably individual. Nevertheless, review of my own experience reveals no reversible error in choosing this product above the alternatives. Accordingly, after considering the evidence accumulated over daily use, comparing it with numerous competing products—including prescription therapies—and giving appropriate weight to both effectiveness and the advantages of a preservative-free formulation, I have found that SYSTANE® Hydration Preservative-Free Lubricant Eye Drops have earned my recommendation.
L**E
I like them cold
I have dry eyes, and this is really been a good product for me I put the packets in the refrigerator and I appreciate that the little top that you twist off can be put back on I usually go through one packet a day, and I leave them in the refrigerator and they are very comforting to my eyes
M**V
Preservative free
Theses eyedrops provide instant relief from dryness, burning, and irritation, and my eyes stay comfortable much longer compared to other brands I’ve used. I also love that they’re preservative-free, which makes them gentle enough to use throughout the day without causing irritation. The single-use vials are convenient, hygienic, and easy to carry in my purse or while traveling. If you struggle with dry eyes, especially from screen time, allergies, or contact lenses. They’ve made a noticeable difference in my daily comfort, and I’ll definitely continue purchasing them.
E**E
Good Product.
After surgery I think it's important to use single use vials and preservative free. These were fine but less of a gel and more just drops.
D**E
Dry eye relief
Great drops for dry eyes. I use in the mornings before putting in contacts. These are a little thicker so it takes a second to settle in. I love the texture.
N**E
Good product, questionable value
The product is great, but Amazon keeps changing the price so I won’t speak to the value My husband uses these every day as his eyes get very dry. It’s safe to use one day at a time and not worry about contamination
B**C
Great dry eye drops
Use them for dry eye. Easy to use and worth the money
Trustpilot
3 days ago
4 days ago