Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

What is the source and function of the Lacto Exosome in Zero Exosome Shot?

The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b

Is it normal for my face to tingle after application?

It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

Do I simply wash it off or do I maintain my regular skincare routine afterwards?

This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?

The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.

Are there any ingredients that should not be used together with it?

There are no restricted ingredients with this product, but those with sensitive skin should be cautious. Perform a patch test and adjust usage based on your skin's reaction

I want to focus on managing my pores. Are there any synergistic products that work well together?

Using Exosome Shot with One-day Serum and Cream improves pore volume by 88% and area by 85% compared to using the shot alone. Apply Exosome Shot, then Serum, and Cream for best results. Results from tests; individual outcomes may vary.

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Medicube Zero 1 Day Exosome Shot 2000ppm - Topical Needle Serum - Pore Firming Lead - Lead-in Solution - Korean Cosmetics

Medicube Zero 1 Day Exosome Shot 2000ppm - Topical Needle Serum - Pore Firming Lead - Lead-in Solution - Korean Cosmetics

Product ID: 725051711

Details

Brand
medicube
Item Form
Gel
Item Volume
0.4 Kilograms
Item Weight
30 Milligrams
Material Feature
Number of Items
1

💧242% absorption boost

🔬clinically low irritation

🧬2000ppm exosome tech

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¥594816

Duties & taxes included

In stock

Sold byAmazon JapanDelivered byDesertcartCustomer service byDesertcartReturns14 days · 30 with PRO

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Description

✨ Unlock flawless skin with science-backed power! 💧

GENTLE YET POTENT FORMULA - Clinically proven low irritation, non-comedogenic, and perfect for sensitive skin types.
NEXT GEN EXOSOME DELIVERY - Harness cutting-edge exosome coat technology for deep, targeted skin rejuvenation.
UNMATCHED ABSORPTION POWER - Boost active ingredient absorption by 242% for visibly hydrated, radiant skin.
SEAMLESS SKINCARE INTEGRATION - Effortlessly fits into your daily routine, enhancing results when paired with Medicube’s AGE-R Booster Pro.
PORE FIRMING SKIN ENERGIZING - Effectively tightens pores while revitalizing skin energy for a fresh, youthful glow.

Medicube Zero 1 Day Exosome Shot is a Korean topical needle serum featuring 2000ppm exosome coat technology that enhances skin absorption by 242%. Clinically tested for low irritation, it firms pores, boosts skin energy, and supports moisture with niacinamide and panthenol. Ideal for all skin types, this gel serum integrates smoothly into daily skincare routines for radiant, healthy skin.

Specifications

ASIN	B0D16L5F2M
Amazon Bestseller	#1,764 in Beauty ( See Top 100 in Beauty ) #51 in Facial Serums
Brand	medicube
Brand Name	medicube
Customer Reviews	4.1 out of 5 stars 2,990 Your Review
Item Form	Gel
Item Volume	0.4 Kilograms
Item Weight	30 Milligrams
Manufacturer	MEDICUBE
Manufacturer Part Number	PMEKR14036
Material Feature	Non-Comedogenic
Material Features	Non-Comedogenic
Model Number	8809981334928
Number of Items	1
Special Ingredients	Collagen
Unit Count	1.0 Count

Reviews

名**し

頑固な開いた毛穴も皮脂毛穴もなくなります

はじめはちょっと痛いですが、数日で頬の毛穴がなくなりました。鼻の毛穴も使用前は皮脂が多くて毛穴の黒ずみが目立つ状態でしたが、毎日使用したところ半月くらいで気がつくとだいぶ目立たなくなりきれいになりました。自分は基本夜の風呂後にメディキューブ→化粧水→美容液→クリームの順で塗っています。気になるときやメイクのりをよくしたいときは朝に塗るときもあります。価格は少し高いかもですが、確実に効果があるように感じていますので、しばらくは購入しようと思います。

29.10.2025

C**E

伸びがいいです。

他の針クリームを塗っていたのですが、今回試しに購入しました。 2000だからかそんなに痛くはないです。劇的な変化はありませんが、伸びもいいし、アンプルとの相性も良いです。

4.06.2025

き**い

もちもちになる

友人の勧めで購入。肌の質感が変わります。つけ始めは少し痛いですが、続けてみたいと思います。

8.05.2026

あ**さ

リピート

お気に入りで何度もリピートしています！

30.01.2026

あ**あ

あんま効果ないよー

これなんかあんまり効果感じなかった。塗り方あってるはずなんだけどなー。別に可もなく不可もなく！！ただ肌荒れはしない！毛穴に効いてる感じはしなかった。

11.05.2026

海**子

とても良かった

8.01.2026

S**O

まだ効果はわからない

使用して2週間。まだ効果なし。チクチク感はあるので期待を持ってもうしばらく使い続けます。

13.09.2025

む**む

幸

私は毛細血管拡張症顔に赤みと血管が見えて，いつも化粧に困難しています，年も年だからと思ってましたが，孫や皆んなに健康な顔を見せたくて頼みました。治りはしませんが，落ち着いて来た様です。低刺激が良かったのだと思います。続けて行ってみようと思います！

13.07.2025

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TrustScore 4.5 | 7,300+ reviews

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