--- product_id: 722855327 title: "Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose" brand: "advantage" price: "¥62809" currency: JPY in_stock: true reviews_count: 5 category: "Advantage" url: https://www.desertcart.jp/products/722855327-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats store_origin: JP region: Japan --- # 2 months protection per dose Kills fleas within 30 min to 4 hrs Naturally derived, award-winning Spinetoram Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose **Brand:** advantage **Price:** ¥62809 **Availability:** ✅ In Stock ## Summary > 🐾 Stay ahead of fleas with Advantage XD—because your cat deserves the best defense! ## Quick Answers - **What is this?** Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose by advantage - **How much does it cost?** ¥62809 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/722855327-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats) ## Best For - advantage enthusiasts ## Why This Product - Trusted advantage brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Rapid Relief:** Starts killing fleas on contact within 30 minutes to 4 hours, stopping bites before they start. - • **Eco-Smart Formula:** Fragrance-free and powered by Spinetoram, a Green Chemistry Award-winning ingredient. - • **Double the Defense:** Each dose delivers 8 weeks of continuous flea protection—twice the duration of typical treatments. - • **Versatile Protection:** Safe for indoor and outdoor cats over 9 lbs and 8 weeks old, keeping your feline friend flea-free year-round. - • **Effortless Application:** Topical spot-on treatment applies in seconds—no pills, no hassle, no prescription needed. ## Overview Advantage XD Large Cat Flea Prevention & Treatment offers 8 months of flea control with 4 topical doses, each providing 2 months of fast-acting, contact-killing protection. Featuring a fragrance-free, naturally derived Spinetoram formula recognized by the US EPA Green Chemistry Challenge, it’s easy to apply and effective for cats over 9 lbs and 8 weeks old, ensuring long-lasting flea prevention for both indoor and outdoor cats. ## Description "Cat lovers choose Advantage XD for double the lasting protection against fleas vs. other 1-month options. Advantage XD for large cats and kittens packs two full months of treatment and continuous protection in each dose, so your cat is protected for longer than the traditional 1-month formula.* If your cat has already tousled with fleas, you’ll love that Advantage XD topical treatment starts killing fleas within 30 minutes to 4 hours through contact so they don’t have to bite and die. And with Advantage XD extended duration formula, that flea prevention remains effective for 8 weeks, outlasting the typical 6-week flea life cycle and preventing reinfestation.Find Advantage XD topical flea treatment available in a variety of pack sizes, from 2 months protection (1 dose), to 4 months protection (2 doses), or 8 months protection (4 doses). This fragrance-free formula contains Spinetoram, a naturally derived, Green Chemistry Award-winning** ingredient.Advantage XD flea infestation prevention is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh over 9 lbs. to use Advantage XD for large cats. Even with the squirmiest of kittens and cats, application is easy. The single, topical, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It's easier, there are no hard-to-swallow pills; this topical treatment goes on in seconds. See product label for more information.For the ultimate convenience in care, Advantage XD is available over the counter – no prescription needed. Once Advantage XD is applied, your cat is ready to get right back to exploring the outdoors or finding a cozy spot for a nap, while you get to enjoy peace of mind.*Based on label claims **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008. " Review: Good product - Good price for flea control. Review: Cat flea medication - This product’s always works. Never had an issue with it or always buy this product. ## Features - 8 months (4 doses) flea treatment and prevention for indoor and outdoor cats and kittens over 9 lbs., 8 weeks or older - Longer-lasting protection vs. other topical products;* 2 months protection per dose, outlasting the typical flea life cycle *Based on label claims - Fast-acting treatment starts killing fleas within 30 minutes to 4 hours through contact - Easy-to-apply topical treatment, no prescription needed - Fragrance-free formula, containing a naturally derived ingredient Spinetoram - winner of a Green Chemistry award** **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0BCX9ZW5V | | Active Ingredients | Spinetoram | | Age Range Description | 8 weeks and older | | Allergen Information | Allergen-Free | | Brand | Advantage | | Brand Name | Advantage | | Customer Reviews | 4.3 out of 5 stars 2,545 Reviews | | Dog Breed Size | Large | | Global Trade Identification Number | 00727804567514 | | Item Form | Topical | | Item Type Name | Topical | | Item Weight | 0.07 Pounds | | Item form | Topical | | Item volume | 8 Milliliters | | Item weight | 0.07 Pounds | | Manufacturer | Advantage | | Manufacturer Part Number | CA4242024AM | | Model Number | CA4242024AM | | Scent | Unscented | | Scent Name | Unscented | | Target Species | Cat | | UPC | 727804567514 | | Unit Count | 4 Count | | Volume | 8 Milliliters | ## Product Details - **Active Ingredients:** Spinetoram - **Brand:** Advantage - **Item form:** Topical - **Item weight:** 32 g - **Scent:** Unscented ## Images ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose - Image 1](https://m.media-amazon.com/images/I/81-XZQvHc3L.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: If this flea product is just microbes why are there the same warmings about poisoning and ingestion as Advantage2 ?** A: IT CAUSED THE FERAL CAT I TAKE CARE OF HAIR TO FALL OUT ONE DAY AFTER APPLICATION HE IS VERY STRONG SO DECIDED NOT TO USE ON MY RESCUE CAT WHO WAY SMALLER HONESTLEY I FEEL ITS JUST AS DANGEROUS GOOD LUCK **Q: Does this kill ear mites** A: No. Mites are related to spiders & harder to kill. Revolution does both. Or get specific ear mite meds **Q: How do you remove the cap?** A: It doesn't have a cap. You just twist the top the way it shows on the side of the tube. I think it's counter clockwise. **Q: Is the only difference between this and Advantage II the time it works fit** A: Hi. Advantage™ XD for cats starts killing fleas in 30 minutes to 4 hours. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Good product *by P***S on 6 May 2026* Good price for flea control. ### ⭐⭐⭐⭐⭐ Cat flea medication *by C***E on 18 April 2026* This product’s always works. Never had an issue with it or always buy this product. ### ⭐⭐⭐⭐ Works but leaves a residue *by C***Y on 13 February 2025* Applied this to my 3 cats about 4 days ago and it appears to have worked! No signs of live fleas on the short haired ones anymore and no side effects to speak of which is great because I was worried about skin irritation from trying a new product. It was easy enough to apply once I realized you didn't have to take the cap completely off and I'm pleased that you only have to apply it once every two months as I am forgetful. My only complaint is that it has been four days and my long haired cat (pictured) still has funky gunky residue on their fur. I applied it at the base of their skull per the instructions and the goo seems to have settled into their hair and is now collecting dust. This is less worrisome for me as my cats don't groom each other but if you have bonded cats this may be a problem as you don't want them ingesting the product. Cleaning it off of my cats neck will also be an issue because washing a cat is a perilous task. ## Frequently Bought Together - Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose - Advantage XD Small Cat Flea Prevention & Treatment For Cats 1.8-9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose - K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 6-Mo Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.jp/products/722855327-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats](https://www.desertcart.jp/products/722855327-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats) --- *Product available on Desertcart Japan* *Store origin: JP* *Last updated: 2026-06-14*