---
product_id: 679536980
title: "Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules)"
brand: "designs for health"
price: "¥54980"
currency: JPY
in_stock: true
reviews_count: 5
category: "Designs For Health"
url: https://www.desertcart.jp/products/679536980-designs-for-health-same-capsules-with-b6-b12-5-mthf
store_origin: JP
region: Japan
---

# 200mg stabilized SAMe 5-MTHF folate + B12 cofactors patented moisture & acid protection Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules)

**Brand:** designs for health
**Price:** ¥54980
**Availability:** ✅ In Stock

## Summary

> 💥 Unlock your body's natural power with stabilized SAMe—because your hormones and mood deserve the best!

## Quick Answers

- **What is this?** Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) by designs for health
- **How much does it cost?** ¥54980 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/679536980-designs-for-health-same-capsules-with-b6-b12-5-mthf)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Conscious Formula:** Non-GMO, gluten-free, dairy-free, soy-free, and vegetarian-friendly—because purity matters in your wellness routine.
- • **Next-Level Absorption Tech:** Patented capsule design shields SAMe from stomach acid, ensuring maximum delivery where it counts—in the small intestine.
- • **Synergistic Cofactor Blend:** Enhanced with bioactive B6, B12, and 5-MTHF folate to optimize SAMe conversion and cellular health.
- • **Precision Methylation Support:** 200mg of stabilized SAMe fuels your body's vital methylation pathways for hormone and neurotransmitter balance.
- • **Trusted by Experts Since 1989:** Over 50,000 physicians rely on Designs for Health for professional-grade supplements backed by cutting-edge science.

## Overview

Designs for Health SAMe Capsules deliver 200mg of stabilized S-Adenosylmethionine combined with essential B vitamins (B6, B12, and 5-MTHF folate) to support immune function, hormone balance, and neurotransmitter synthesis. Featuring patented technology that protects SAMe from degradation, these non-GMO, gluten-free capsules ensure superior absorption and efficacy. Trusted by healthcare professionals since 1989, this vegetarian-friendly formula promotes cellular health and overall well-being.

## Description

SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors B12 and folate. SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage. These capsules provide 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF in order to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine.

Review: These are amazing pills. If you're at all concerned with proper methylation of hormones in your body THESE are a must have. I started taking these under the advice of a physician. They are an extremely valuable component in the successful balancing of hormone levels in women. I've had cancer twice.. I'm estrogen dominant, so preventing the mess that comes with a hormone balancing act in a body that it prone to cause problems these pills can make all the difference. If you are taking hormones please consult your doctor before taking these. I realize they're over the counter, but do not let that fool you. Some of these nutraceuticals are extremely serious business. But if you've been struggling with unsuccessful in getting your body to respond correctly, these just might make all the difference.
Review: It is difficult to identify specific benefits of this item as my prescription for supplements includes 14 others but it seems to be helping my overall well being by reducing RA pains to be at tolerable level without undesired side effects of RA medications. It is a relief to be medcine free for chronic illness such as RA. Combined with prescribed diet and swimming 6000 yards a week, I feel pretty good for a RA suffer at age 78.

## Features

- Immune And Hormone Support - S-Adenosylmethionine or SAMe is a naturally occurring compound found in the human body as well as in plant and animal foods. It is involved in many processes throughout the body. SAMe plays a role in supporting the immune system and maintaining cell membranes, the protective barrier that surrounds all cells. It also helps to produce neurotransmitters like melatonin- that helps with your body's sleep cycle, and serotonin, the "feel good" hormone. *
- Includes Necessary Cofactors - Each capsule provides 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. *
- Special Technology - Our SAMe capsules are made using special technology with a patented stabilized powder which protects the SAMe from being destroyed by air and moisture. This cutting-edge technology prevents its breakdown by stomach acidity and allows the capsule to be absorbed intact in the small intestine. *
- Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*
- Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00B9EV16I |
| ASIN  | B00B9EV16I |
| Age Range Description | Adult |
| Brand Name | designs for health |
| Container Type | Bottle |
| Customer Reviews | 4.8 4.8 out of 5 stars (30) |
| Customer reviews | 4.8 4.8 out of 5 stars (30) |
| Diet Type | Gluten Free, Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions | 6.5 x 6.5 x 12.1 centimeters |
| Item Form | Capsule |
| Item Weight | 240 g |
| Manufacturer | Designs for Health |
| Manufacturer  | Designs for Health |
| Manufacturer Part Number | SAM090 |
| Manufacturer reference  | SAM090 |
| Material Features | Gluten Free |
| Material Type Free | Dairy Free, GMO Free, Soy Free |
| Model Name | Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) |
| Number of Items | 1 |
| Primary Supplement Type | SAMe Capsules |
| Product Benefits | Brain Health Support |
| Product Dimensions  | 6.5 x 6.5 x 12.07 cm; 240.4 g |
| Special Ingredients | 200mg Stabilized SAMe |
| Specific Uses For Product | Immune System,Immune |
| UPC | 879452003774 |
| Unit Count | 90.0 Count |

## Product Details

- **Brand:** designs for health
- **Diet type:** Gluten Free, Vegetarian
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 6.5 x 6.5 x 12.1 centimeters
- **Item form:** Capsule
- **Item weight:** 240 g
- **Primary supplement type:** SAMe Capsules
- **Product benefits:** Brain Health Support
- **Special ingredients:** 200mg Stabilized SAMe
- **Unit count:** 90.0 Count

## Images

![Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) - Image 1](https://m.media-amazon.com/images/I/71T5WaNk8tL.jpg)
![Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) - Image 2](https://m.media-amazon.com/images/I/71vxf-h1TUL.jpg)
![Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) - Image 3](https://m.media-amazon.com/images/I/71fPwhNrpvL.jpg)
![Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) - Image 4](https://m.media-amazon.com/images/I/71+CwR5DKhL.jpg)
![Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules) - Image 5](https://m.media-amazon.com/images/I/51x4GEWYDBL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by A***R on 25 August 2015*

These are amazing pills. If you're at all concerned with proper methylation of hormones in your body THESE are a must have. I started taking these under the advice of a physician. They are an extremely valuable component in the successful balancing of hormone levels in women. I've had cancer twice.. I'm estrogen dominant, so preventing the mess that comes with a hormone balancing act in a body that it prone to cause problems these pills can make all the difference. If you are taking hormones please consult your doctor before taking these. I realize they're over the counter, but do not let that fool you. Some of these nutraceuticals are extremely serious business. But if you've been struggling with unsuccessful in getting your body to respond correctly, these just might make all the difference.

### ⭐⭐⭐⭐⭐ Review
*by T***E on 20 March 2015*

It is difficult to identify specific benefits of this item as my prescription for supplements includes 14 others but it seems to be helping my overall well being by reducing RA pains to be at tolerable level without undesired side effects of RA medications. It is a relief to be medcine free for chronic illness such as RA. Combined with prescribed diet and swimming 6000 yards a week, I feel pretty good for a RA suffer at age 78.

### ⭐⭐⭐⭐⭐ Review
*by E***. on 8 November 2017*

This product has helped me significantly. I am a healthy 40-yr-old and started experiencing neuralgia in extremities. My naturopathic doctor diagnosed me with anxiety/depressed and recommended this product. My symptoms are lessening and hoping they disappear completely. I’m thankful this product is available over turning to an prescription with side effects. The main side effect of this product as been some nausea and gas which appears to be improving.

## Frequently Bought Together

- Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (90 Capsules)
- Designs for Health Vitamin D Supreme - Vitamin D 5000 IU with 2000mcg Vitamin K as MK4 for Bone Health, Heart Health & Immune Support - Vitamin D3 Enhanced with GG Supplement (60 Capsules)
- Designs for Health N-Acetyl-L-Cysteine - 900mg NAC, Antioxidant Glutathione Precursor - Detox + Workout Recovery Support - Non-GMO + Gluten Free Supplement (120 Capsules)

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---

*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-05-12*