---
product_id: 661970350
title: "Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct"
brand: "tylenol"
price: "¥3592"
currency: JPY
in_stock: true
reviews_count: 8
category: "Tylenol"
url: https://www.desertcart.jp/products/661970350-tylenol-extra-strength-severe-cough-sore-throat-day-and-night
store_origin: JP
region: Japan
---

# 500mg acetaminophen max strength 24 caplets combo pack 16 day + 8 night caplets Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct

**Brand:** tylenol
**Price:** ¥3592
**Availability:** ✅ In Stock

## Summary

> 💥 Knock out cough & sore throat 24/7 with Tylenol’s power-packed day & night duo!

## Quick Answers

- **What is this?** Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct by tylenol
- **How much does it cost?** ¥3592 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/661970350-tylenol-extra-strength-severe-cough-sore-throat-day-and-night)

## Best For

- tylenol enthusiasts

## Why This Product

- Trusted tylenol brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Compact Combo Pack:** Perfectly sized 24-count box to keep your sick care essentials ready and stocked
- • **All-Day & Night Relief:** 16 daytime caplets keep you sharp, 8 nighttime caplets help you rest easy
- • **Fast-Acting & Easy to Take:** Capsules designed for quick absorption and hassle-free dosing every 6 hours
- • **Powerful Multi-Symptom Formula:** Extra strength acetaminophen + cough suppressant + antihistamine for total cold & flu control
- • **Trusted Doctor-Recommended Brand:** Tylenol, #1 pain relief brand trusted by healthcare pros

## Overview

Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets deliver targeted, multi-symptom relief with 500 mg acetaminophen for pain and fever, 15 mg dextromethorphan HBr to suppress cough, and chlorpheniramine maleate to ease runny nose at night. This 24-count combo pack includes 16 daytime and 8 nighttime caplets, designed for adults and children 12+, providing trusted, fast-acting relief to keep you productive by day and rested by night.

## Description

Stop your cough and sore throat before they stop you with Extra Strength Tylenol Severe Cough + Sore Throat Day/Night tablets. These extra-strength pain relief tablets provide powerful multi-symptom cold and flu relief all day. These symptoms include headaches, body aches, fever, painful sore throat, and coughs. This combo pack includes 16 day caplets formulated with 500 mg of extra strength acetaminophen for effective pain relief and 15 mg of dextromethorphan HBr cough suppressant to help calm your severe cough and 8 night caplets with chlorpheniramine maleate, a powerful antihistamine to help relieve your runny nose. This extra-strength cold relief medicine is available over the counter and can be used by adults as well as children 12 and older. Take two caplets every six hours while symptoms last and do not exceed six caplets in 24 hours. Help combat cold and flu symptoms with the power of extra strength acetaminophen from Tylenol, the #1 doctor recommended pain relief brand.

Review: My Go-To when I'm sick - Whenever I get sick, this Tylenol Severe Cough & Sore Throat combo pack is my absolute go-to. It knocks out sore throat pain fast, helps clear up congestion, and makes it way easier to get through the day (and sleep better at night). The day caplets keep me functioning, while the night ones help me actually rest without constant coughing. It’s easy to take, works quickly, and really helps when my throat feels like sandpaper and my head feels stuffy. I always keep a box on hand just in case—because when I need relief, this never lets me down. If you’re looking for something that actually works when you're sick, this is the one to grab.
Review: Works in pill and liquid. Liquid is a “terrible awful” for anyone that watched the movie the help - Works. Enough said! FYI though, the liquid version is legit awful, taste wise. I can’t explain it, about makes me gag. I have to sip it and chase each sip with juice. A full medicine cup of it takes me 4-5 sips before I can get it down. POINT BEING SAVE YOURSELF FROM DRY HEAVES AND BUY THE PILLS. GO NOW! Get early because they sometimes sell out even online.. If you’re on a budget, the generic version works just as well

## Features

- 24-count combo pack, 16 day & 8 night caplets, of Extra Strength Tylenol Severe Cough + Sore Throat Day & Night caplets with acetaminophen & dextromethorphan HBr for powerful, multi-symptom relief for your painful sore throat & cough all day & night
- Extra strength pain reliever & fever reducer + cough suppressant caplets help temporarily relieve your daytime or nighttime cold symptoms like head & body aches, fever & sore throat, & painful coughs, plus, relief from your runny nose at night
- The maximum-strength, multi-symptom cold & flu medicine is formulated with 500 mg of extra strength acetaminophen to help relieve aches & pains & reduce fever, plus, 15 mg of dextromethorphan HBr cough suppressant to help calm your severe cough
- Say goodnight to your cough & sore throat. The nighttime cold medicine also contains chlorpheniramine maleate, a powerful antihistamine to help relieve your runny nose. Available over the counter, keep this combo pack with your sick care supplies
- Get fast, multi-symptom cold and flu relief with the power of extra strength acetaminophen from Tylenol, the #1 doctor recommended pain relief brand. For adults & children 12 years and older, take two caplets every six hours while symptoms last

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0DG9BW8WP |
| Best Sellers Rank | #15,956 in Health & Household ( See Top 100 in Health & Household ) #147 in Cold & Flu Medicine |
| Customer Reviews | 4.8 4.8 out of 5 stars (522) |
| Date First Available  | September 6, 2024 |
| Manufacturer  | Johnson & Johnson |
| Product Dimensions  | 0.75 x 2.88 x 4.47 inches; 1.13 ounces |

## Product Details

- **Active Ingredients:** Acetaminophen, Dextromethorphan
- **Brand:** Tylenol
- **Item dimensions L x W x H:** 0.75 x 2.88 x 4.47 inches
- **Product Benefits:** Cough Relief
- **Specific Uses For Product:** Cough, Sore Throat

## Images

![Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct - Image 1](https://m.media-amazon.com/images/I/81xwnQcJr1L.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ My Go-To when I'm sick
*by A***Z on June 5, 2025*

Whenever I get sick, this Tylenol Severe Cough & Sore Throat combo pack is my absolute go-to. It knocks out sore throat pain fast, helps clear up congestion, and makes it way easier to get through the day (and sleep better at night). The day caplets keep me functioning, while the night ones help me actually rest without constant coughing. It’s easy to take, works quickly, and really helps when my throat feels like sandpaper and my head feels stuffy. I always keep a box on hand just in case—because when I need relief, this never lets me down. If you’re looking for something that actually works when you're sick, this is the one to grab.

### ⭐⭐⭐⭐⭐ Works in pill and liquid. Liquid is a “terrible awful” for anyone that watched the movie the help
*by M***J on August 18, 2025*

Works. Enough said! FYI though, the liquid version is legit awful, taste wise. I can’t explain it, about makes me gag. I have to sip it and chase each sip with juice. A full medicine cup of it takes me 4-5 sips before I can get it down. POINT BEING SAVE YOURSELF FROM DRY HEAVES AND BUY THE PILLS. GO NOW! Get early because they sometimes sell out even online.. If you’re on a budget, the generic version works just as well

### ⭐⭐⭐⭐⭐ Best cold medicine
*by J***Z on January 6, 2026*

Helped my son heal from his cold so fast.

## Frequently Bought Together

- Tylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct
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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-01-26*