Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

Is it normal for my face to tingle after application?

It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

Do I simply wash it off or do I maintain my regular skincare routine afterwards?

This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

Are there any ingredients that should not be used together with it?

There are no restricted ingredients with this product, but those with sensitive skin should be cautious. Perform a patch test and adjust usage based on your skin's reaction

I want to focus on managing my pores. Are there any synergistic products that work well together?

Using Exosome Shot with One-day Serum and Cream improves pore volume by 88% and area by 85% compared to using the shot alone. Apply Exosome Shot, then Serum, and Cream for best results. Results from tests; individual outcomes may vary.

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medicube Zero Exosome Shot 7,500 PPM Spicule Facial Serum | Liquid Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz

Product ID: 647986939

Details

Product benefits
Pore Treatment
Scent
Aloe
Skin type
All
Special ingredients
alpha_hydroxy
Use for
Face

💉7,500 PPM micro-needle spicules for precision delivery

💧242% enhanced absorption & hydration boost

🔬15M patented Exosome shots for deep skin regeneration

¥2059

Duties & taxes included

In stock

Sold byAmazon JapanDelivered byDesertcartCustomer service byDesertcartReturns14 days · 30 with PRO

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Description

✨ Glow Like You Mean It — The Future of Skincare is Here! 💧

HYDRATION MULTIPLIER EFFECT - Boost your skin’s moisture retention by 242%, thanks to a potent blend of Niacinamide and Panthenol for a plump, radiant glow.
NEXT GEN EXOSOME TECHNOLOGY - Harness patented 15 million Exosome shots that revitalize skin vitality and texture from within, setting you apart in the skincare game.
SEAMLESS ROUTINE INTEGRATION - Effortlessly elevate your daily skincare with a simple 3-step process, perfectly compatible with advanced tools like the AGE-R Booster Pro.
CLINICALLY VALIDATED GENTLE - Formulated for all skin types, including sensitive skin, with non-comedogenic, gluten-free, and low-irritation assurance.
PRECISION MICRO NEEDLING POWER - Experience targeted pore penetration with ultra-fine spicules delivering active ingredients exactly where your skin needs them.

medicube Zero Exosome Shot is a cutting-edge Korean facial serum featuring 7,500 PPM micro-needle spicules and 15 million patented Exosome shots that deliver active ingredients deep into pores. Clinically proven to enhance absorption by 242%, it combines AHA, BHA, PHA, Niacinamide, and Panthenol to improve skin texture, pore care, and hydration. Suitable for all skin types, this gentle yet powerful serum offers microneedling-like results without irritation, making it a must-have for radiant, healthy skin.

Specifications

ASIN	B0D137TMRB
Best Sellers Rank	#685 in Beauty ( See Top 100 in Beauty ) #21 in Facial Day Care
Brand	medicube
Brand Name	medicube
Country of Publication	Korea, Republic of
Customer Reviews	4.5 out of 5 stars 5,717 Reviews
Item Form	Drop
Item Volume	30 Milliliters
Item Weight	45 Grams
Manufacturer	APR
Manufacturer Part Number	PMEKR14040
Material Features	Gluten, Oven, Comedo, Artificial Color
Model Number	8809982768524
Number of Items	1
Product Benefits	Pore Treatment
Product benefits	Pore Treatment
Scent	Aloe
Scent Name	Aloe
Skin Tone	All
Skin Type	All
Skin type	All
Special Ingredients	alpha_hydroxy, collagen, minerals
Special ingredients	alpha_hydroxy, collagen, minerals
Target Use Body Part	Face
Unit Count	1 Count
Use for	Face

Reviews

Z**T

Instant Glow with Micro-needling, Like Results

Amazing product! I applied it at night and woke up with baby-soft skin and a healthy, radiant glow from the very first use. It delivers results similar to microneedling—I’m definitely adding it to my skincare essentials!” 👏👏

3.08.2025

H**D

Best product

I have acne prone skin i read the reviews of this product and ordered it worked on my skin even in one week unbelievable results I will definitely buy it again

24.11.2025

S**A

I see changes in 7 days

Love it

11.02.2026

A**A

Love it!

While applying I felt tingling, just like millions of needles running over my face! After that I applied medicine serum and night peel mask. Love the results, skin looks plump and moist in the morning. It’s a must have for me from now on!

7.02.2025

A**A

Good one

Looks like it’s working:)

19.01.2026

S**A

مميز

بيعطي وخزات كالابر بس لسه قيد التجربة

2.02.2026

K**M

Efficient!

Excellent product!

14.12.2025

S**N

Too aggressive for my skin

I wanted to trial it for congestion and pores. For reference, I am a regular user of acids, retinols and had chemical peels. This was probably on par with having a chemical peel. It certainly does exfoliate and deep cleanse my face. However, it does also disrupt your skin barrier and sensitise it after. I will finish it up as I don't like wasting money, but I use a lot of soothing barrier products after. I would not buy it again as there are other gentler effective exfoliation available. I think it is better suited to younger, oilier thicker resilient skin.

4.07.2025

R**A

Almost immediate results

Though the needle tingling lasts a while, yet u feel almost immediate results! Just use a good moisturizer afterwards. Amazing!

24.02.2026

T**E

Ça pique

Me convient bien pour l'instant. J'attends de voir les résultats sur la durée. Ça pique fort quand même.

19.08.2026

B**N

Das ideaal voor al huid

Geweldig

18.10.2025

S**N

Excellent

10.05.2026

J**O

super

das wirkt echt stark

2.09.2026

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TrustScore 4.5 | 7,300+ reviews

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