--- product_id: 635096637 title: "Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested" brand: "science" price: "¥16694" currency: JPY in_stock: true category: "Renue By Science" url: https://www.desertcart.jp/products/635096637-renue-by-science-trigonelline-high-strength-trigonelline-trg-methylated-niacin store_origin: JP region: Japan --- # 250mg Trigonelline per capsule Crosses blood-brain barrier for brain & muscle NAD+ Supports DNA repair & cellular integrity Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested **Brand:** science **Price:** ¥16694 **Availability:** ✅ In Stock ## Summary > ⚡ Unlock your cellular power with Trigonelline — the future of youthful energy! ## Quick Answers - **What is this?** Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested by science - **How much does it cost?** ¥16694 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/635096637-renue-by-science-trigonelline-high-strength-trigonelline-trg-methylated-niacin) ## Best For - science enthusiasts ## Why This Product - Trusted science brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Molecular Guardian:** Promotes DNA repair and healthy gene expression with methyl donation. - • **Muscle Energy Amplifier:** Boosts NAD+ synthesis in muscles for enhanced cellular energy and recovery. - • **Plant-Powered Longevity:** Derived from natural sources like coffee and fenugreek, ensuring high bioavailability and systemic delivery. - • **Age-Defying Tissue Support:** Refuels heart, brain, and muscle tissues to preserve youthful strength and cognition. - • **Flushing-Free Niacin Alternative:** Stable, bioavailable NAD+ precursor without the common niacin flush. ## Overview Renue By Science Trigonelline delivers a potent 250mg dose of a methylated niacin derivative that uniquely supports NAD+ synthesis across muscle, brain, and heart tissues. This non-GMO, third-party tested supplement promotes DNA repair, cellular energy, and longevity without the flushing side effects typical of niacin. Made in the USA, it offers a stable, bioavailable formula that crosses the blood-brain barrier, fueling your body’s vital systems for sustained strength and cognitive health. ## Description Buy Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested on desertcart.com ✓ FREE SHIPPING on qualified orders ## Features - Muscle NAD+ Synthesis: By promoting NAD+ synthesis in muscle through the Preiss-Handler pathway, Trigonelline enhances cellular energy and repair, supporting overall health and longevity. Supports muscle NAD+ production, unlike NMN or NR. It provides the precursors needed to generate NAD+ that becomes depleted through cellular metabolism and aging. - DNA Repair and Cellular Integrity: Encouraging cellular repair and maintaining DNA integrity, Trigonelline protects against cellular damage and promotes health at the molecular level. Additionally donates methyl groups which promote healthy gene expression. - Protects Against Tissue Aging: Supplies much-needed NAD+ precursors to tissues like the heart, brain, and muscles. NAD+ declines fastest in tissues that experience the most oxidative damage and physiological use, so using Trigonelline to refuel these tissues protects youthful heart, brain, and muscle function, preserving strength and cognition. - Broad Longevity Support: Unlike other NAD+ precursors, Trigonelline is stable through digestion and enters circulation for systemic tissue delivery. Once in circulation it can support healthy sugar and lipid metabolism and does not cause the flushing effect that many experience with niacin. - Naturally Occurring NAD+ Support: Trigonelline is found in numerous plant foods including coffee and fenugreek. This highly bioavailable and stable molecule can cross the blood-brain barrier and is quickly metabolized into NAD+, measurably impacting circulating and intracellular levels of this critical molecule. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0D74QBVQG | | Age Range Description | Adult | | Best Sellers Rank | #166,413 in Health & Household ( See Top 100 in Health & Household ) #264 in Vitamin B3 (Niacin) Supplements | | Brand | Renue By Science | | Brand Name | Renue By Science | | Container Type | Bottle | | Customer Reviews | 4.0 out of 5 stars 39 Reviews | | Dosage Form | Capsule | | Flavor | Unflavored | | Item Dimensions | 2.36 x 2.36 x 4.33 inches | | Item Form | Capsule | | Item dimensions L x W x H | 2.36 x 2.36 x 4.33 inches | | Manufacturer | Renue By Science | | Manufacturer Part Number | 850055685277 | | Number of Items | 1 | | Primary Supplement Type | Trigonelline | | Product Benefits | Muscle Growth | | Recommended Uses For Product | Supporting muscle NAD+ production, DNA repair, protecting against tissue aging, and promoting healthy sugar and lipid metabolism | | Total Servings Per Container | 90 | | UPC | 850055685277 | | Unit Count | 90 Count | ## Product Details - **Age Range (Description):** Adult - **Brand:** Renue By Science - **Flavor:** Unflavored - **Item Form:** Capsule - **Item dimensions L x W x H:** 2.36 x 2.36 x 4.33 inches - **Number of Items:** 1 - **Package Information:** Bottle - **Primary Supplement Type:** Trigonelline - **Product Benefits:** Muscle Growth - **Unit Count:** 90 Count ## Images ![Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested - Image 1](https://m.media-amazon.com/images/I/51E8LVfEWnL.jpg) ![Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested - Image 2](https://m.media-amazon.com/images/I/61l7jk-JFdL.jpg) ![Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested - Image 3](https://m.media-amazon.com/images/I/61sYlyiQAoL.jpg) ![Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested - Image 4](https://m.media-amazon.com/images/I/61qnMljTakL.jpg) ![Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in the USA & Third-Party Tested - Image 5](https://m.media-amazon.com/images/I/715Oh25vq+L.jpg) ## Frequently Bought Together - Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in The USA & Third-Party Tested - L-Ergothioneine 25mg - 120 Vegetarian Capsules, 4-Month Supply, Antioxidant Supplement for Wellness Routine, GMP Certified, Made in USA - NatureBell Korean Red Ginseng 2,250mg Per Serving, 240 Softgels | Panax Ginseng Root, Standardized to 10% Ginsenosides, Non-GMO, Support Energy, Male Performance, & Immune System --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.jp/products/635096637-renue-by-science-trigonelline-high-strength-trigonelline-trg-methylated-niacin](https://www.desertcart.jp/products/635096637-renue-by-science-trigonelline-high-strength-trigonelline-trg-methylated-niacin) --- *Product available on Desertcart Japan* *Store origin: JP* *Last updated: 2026-10-22*