

💧 Unlock flawless skin with the power of 15M micro-boosts!
The Zero Exosome Shot 7,500 PPM Spicule Facial Serum is a cutting-edge Korean skincare booster featuring 15 million patented Exosome shots delivered via micro-needle spicules. It combines AHA, BHA, and PHA acids for gentle exfoliation, enhances active ingredient absorption by 242%, and is clinically tested to be gentle on all skin types. Designed for pore care, skin texture improvement, and hydration, it integrates seamlessly into advanced skincare routines for visible, radiant results.
























| ASIN | B0D137TMRB |
| Best Sellers Rank | #11 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1 in Facial Serums |
| Brand | medicube |
| Brand Name | medicube |
| Customer Reviews | 4.5 out of 5 stars 6,963 Reviews |
| Item Form | Ampoule |
| Item Height | 12 centimeters |
| Item Volume | 30 Milliliters |
| Item Weight | 91 Grams |
| Manufacturer | Medicube |
| Number of Items | 1 |
| Product Benefits | Pore Treatment |
| Recommended Uses For Product | Pore Care,Exfoliation,Improving Skin Texture |
| Scent | Aloe |
| Scent Name | Aloe |
| Skin Tone | All |
| Skin Type | Acne Prone, All, Combination, Dry, Sensitive |
| Special Ingredients | alpha_hydroxy, collagen, minerals |
| Target Use Body Part | Face |
| Unit Count | 1.01 Fluid Ounces |
| Use for | Face |
K**E
Very Good. Not a "beginner strength" product. Prepare for prickling.
If you're familiar at all with microneedling, this is the same idea. There are little spicy led (to y dissolving needles) in this serum that make micro channels in your skin to allow products to penetrate more deeply. It also has three gentle chemical exfoliants to smooth and brighten skin. It's a fairly thick, non-sticky serum, and it prickles quite a bit when you massage it in. I bought this on a whim and found out later that this is NOT "beginner strength". A starter serum would be a 100 ppm level. 2000 is definitely more intense and I do get some irritation immediately afterward. I own a professional grade microneedling machine, but between setting it up and sterilizing, it just feels like more of a project than I want to do for shallow, frequent needling. This serum is a nice shortcut and really, really speeds up the results I see from other products, and I use it roughly o CD a week.
A**E
Yes this product does work very well with an already established skincare routine.
Ima be honest, I was skeptical on how well this product works after hearing it all over tiki tok but they are definitely onto something. I got the exosome 2000 yesterday and used it the same night. I admit, yes it does itch and sting but its tolerable and went away after like 30 - 45 mins of using. It didnt make my skin red, which was surprising. My current routine is: Pm only; - anua oil cleanser - anua deep pore cleanser - anua 70 toner - (now) medicue one day exosome shot 2000 - (now) corsx vitamin c 23 - corsx snail mucin essence - Neutrogena firm moisturizer or anua daily lotion [ i like to switch between the two ] Im 31 years old, my skin is textured with dark spots, dull and I have a chubby face with few fine lines, scars and huge pores on the apples of my cheeks and some on my nose. I get millia under my eyes/ on the top of my cheek sometimes. Its not too close to the thin skin under my eyes. Today ( the next morning) I noticed my pore are visibly smaller. Wow really?! Yes really! even after 1 use. It's like an exfoliant that my skin needed. (Paula's choice bha, aha exfoliating toner sucks and did not work for me). I noticed my skin was softer and the Milia looks like it opened up and the ball inside is ready to fall out. This product will become part of my skincare routine for sure! I will repurchase and highly suggest this product.
H**S
Timeless beauty in a bottle
I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉
J**R
Not a miracle worker, but a decent product
If you’re on social media then you’ve probably seen the entire medicube line hyped up. I was out my normal products so I decided to give this line a try. I tried the 2000 vs the 7500 because my skin is a bit sensitive. It’s easy to apply and gentle enough to use daily. I apply after cleansing but before serums. It does feel a bit prickly, but not uncomfortable. I’ve been using it for 2-3weeks now and I feel like my pores actually look more enlarged…I’m assuming this may just be from helping clean them out? I wasn’t expecting a miracle, but from some of the other reviews I slightly expected a drastic change in my skin appearance and/or texture. While it has improved some, it’s far from drastic. I have been combining it with the pore cleanser and pink serum from medicube in addition to my moisturizers and tretinoin. It’s not expensive, so I think it’s ok for the price, but it’s not a miracle worker. I’ll continue to use the entire vial and then probably purchase the 7500 and see if it makes any difference. The serum goes on lightweight and dries down nicely.
M**E
Effective texture booster that doesn’t feel too intense (every-other-night)
I’ve been using the Medicube Zero Exosome Shot 7,500 PPM spicule serum at night every other night, and I’m impressed. It has a light prickly/tingly feel like you’d expect, but for me it’s not too painful and it settles down quickly. After a few uses, my skin already looks smoother and feels more even, especially in areas where I notice texture and pores. How I’m using it: clean, dry skin → thin layer → simple moisturizer. Tip: I keep the rest of my routine gentle on the nights I use this (no extra strong actives). Bottom line: 5 stars so far. It feels like it’s actually working without being miserable to use.
L**A
7500 & No pain, love this light serum, doesn’t pill and I used shot mode first & booster mode with
This is a great serum, I was kind of afraid of trying it at first since I bought the higher level version at 7500 and reading reviews saying that it hurt to put on but once I did try it I was very happily surprised. My skin had a glow to it after application and there was no pain when applying. I rubbed it on my face, cheek to check then forehead then patted it on my face to absorb better and it was more like a very light tingly feeling but only when I patted the spot I was applying the serum to. This isn’t sticky on my skin, there isn’t a scent to it and it’s not painful, it’s also very light weight and comes out of the pump looking like a thin see though gel looking serum so this is one I use first before my pdrn collagen serum or any of my other Medicube serums because this EXO serum seems to be the lightest and very helpful to your skin and pores. This 7500 EXO feels very hydrating as well, I put it on and took a nap and when I woke it felt like a moisturizer on my face but didn’t rub of onto my pillows as it went into my skin, I touched my face and could still feel the very light tingle ( I can’t think of a different name then tingle but it’s more like when you pat or rub it into your face you can feel a light sensation on you face, it’s quite pleasant though.) I am so glad I didn’t purchase the 2000 version because the 7500 it just perfect. You can feel it’s on your face but no pain, I also made sure to use the booster pro age-r on shot mode and used the pore toner pads before. I have sensitive skin and this didn’t bother my face but if you have extremely sensitive skin then maybe try the 2000 first. It really depends on your skin. Personally I wouldn’t waste on the 2000 and just buy the 7500 because it is so light feeling even though you can still feel it, it kinda feels nice when applying. This doesn’t pill on your face if you want to use the booster mode after or apply another serum over it. I used the salmon pdrn serum on booster mode after I waited about 30 minutes for the pore shot serum to dry, I then used the booster mode after for the pore shot by putting it on level 2 and moving it up towards my forehead and still no pain,. Then used the salmon pdrn serum ( highly recommend! ) over it, finishing the 5 min for booster mode and had a lovely glow with pink cheeks. I wish I tried this exosome spicule shot a long time ago, it’s lovely and not painful but you can feel and tell it’s working on your face. I finished with the cooling jelly moisturizer and a collagen liquid mask once the 2 ( patted on my face by hand ) layers of moisturizer had dried. The next day my face felt and looked great with a nice glow to it and a glasssy finish which I absolutely love about the Medicube products, they due all work and makes your face look younger, also helps get rid of fine lines. This serum is an amazing product to start with after applying the toner pad and if you have a shot mode appliance by Medicube make sure to due that first ( before toner ) because it opens your pores and helps the serum penetrate deeper as does the booster mode, it helps your products go deeper into your skin and also helps the serums dry faster as they penetrate your skin deeper, saves time when you’re doing your night routine and is now a staple for me each night. Great skincare products! I love Medicube products and they actually work as well at a great price point compared to other brands. I always update my reviews if something changes, so if my opinion changes about this product I will be updating. For now I can’t wait to try the salmon pdrn EXO shot next!
C**C
the absolute best skincare on the market
this is the only skincare i use i have dry sensitive skin and this brand is phenomenal i actually see results and keep seeing results it is the healthiest and prettiest my skin has been i get compliments all the time on my skin it is glowing and my cosmetics lay perfectly and flawless on my skin now i cannot say enough good things about medicube
T**.
Effective
Very effective - but stings. The reason for the “prickly” feel is because the skin barrier is compromised, but the sensation fades quickly. Doesn’t leave a sticky residue, is thinner in consistency, and it’s more easily absorbed. Highly recommend!
Trustpilot
1 week ago
1 month ago