---
product_id: 621913111
title: "medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz"
brand: "medicube"
price: "¥7097"
currency: JPY
in_stock: true
reviews_count: 9
category: "Medicube"
url: https://www.desertcart.jp/products/621913111-medicube-exosome-shot-zero-7-500-ppm-spicule-facial-serum
store_origin: JP
region: Japan
---

# 242% enhanced absorption 15M patented Exosome shots 7,500 PPM Spicule serum strength medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz

**Brand:** medicube
**Price:** ¥7097
**Availability:** ✅ In Stock

## Summary

> ✨ Unlock your skin’s future with the power of 15M micro-boosts!

## Quick Answers

- **What is this?** medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz by medicube
- **How much does it cost?** ¥7097 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/621913111-medicube-exosome-shot-zero-7-500-ppm-spicule-facial-serum)

## Best For

- medicube enthusiasts

## Why This Product

- Trusted medicube brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Supercharged Absorption:** Formulation enhances ingredient uptake by 242%, maximizing hydration and skin barrier repair with Niacinamide & Panthenol.
- • **Precision Micro-Targeting:** 15 million patented Exosome shots deliver active ingredients directly into pores for laser-focused skin transformation.
- • **Next-Gen Exosome Technology:** Exosome-coated spicules penetrate deeply, revitalizing skin texture and boosting vitality like no other serum.
- • **Clinically Validated & Gentle:** Non-comedogenic, low-irritation, gluten-free formula clinically tested for all skin types, including sensitive skin.
- • **Effortless Routine Integration:** Seamlessly fits into your skincare ritual with a simple 3-step process, amplifiable with Medicube’s AGE-R Booster Pro.

## Overview

Medicube Exosome Shot Zero is a cutting-edge Korean liquid skin booster serum featuring 7,500 PPM spicules and 15 million patented Exosome shots. Designed for professional-grade pore care and skin texture refinement, it uses advanced Exosome-coated technology to deliver active ingredients deep into the skin. Clinically proven to enhance absorption by 242%, it combines AHA, BHA, PHA, Niacinamide, and Panthenol for superior hydration and barrier support. Suitable for all skin types, this serum offers a potent, needle-free microneedling effect that visibly rejuvenates skin, reduces pores, and promotes a radiant, youthful glow.

## Description

desertcart.com: medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz : Beauty & Personal Care

Review: Very Good. Not a "beginner strength" product. Prepare for prickling. - If you're familiar at all with microneedling, this is the same idea. There are little spicy led (to y dissolving needles) in this serum that make micro channels in your skin to allow products to penetrate more deeply. It also has three gentle chemical exfoliants to smooth and brighten skin. It's a fairly thick, non-sticky serum, and it prickles quite a bit when you massage it in. I bought this on a whim and found out later that this is NOT "beginner strength". A starter serum would be a 100 ppm level. 2000 is definitely more intense and I do get some irritation immediately afterward. I own a professional grade microneedling machine, but between setting it up and sterilizing, it just feels like more of a project than I want to do for shallow, frequent needling. This serum is a nice shortcut and really, really speeds up the results I see from other products, and I use it roughly o CD a week.
Review: Timeless beauty in a bottle - I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉

## Features

- Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
- Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
- Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
- Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
- Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicube’s Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0D137TMRB |
| Best Sellers Rank | #302 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #12 in Facial Serums |
| Customer Reviews | 4.5 4.5 out of 5 stars (7,497) |
| Item model number  | 8809982768524 |
| Manufacturer  | Medicube |
| Product Dimensions  | 1.77 x 1.77 x 4.72 inches; 3.21 ounces |

## Product Details

- **Product Benefits:** Pore Treatment
- **Scent:** Aloe
- **Skin Type:** Acne Prone, All, Combination, Dry, Sensitive
- **Special Ingredients:** alpha_hydroxy, collagen, minerals
- **Use for:** Face

## Images

![medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz - Image 1](https://m.media-amazon.com/images/I/71I6MkG0fyL.jpg)

## Available Options

This product comes in different **Color, Size** options.

## Questions & Answers

**Q: What are exosomes?**
A: Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

**Q: What is the source and function of the Lacto Exosome in Zero Exosome Shot?**
A: The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b

**Q: Is it normal for my face to tingle after application?**
A: It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

**Q: Do I simply wash it off or do I maintain my regular skincare routine afterwards?**
A: This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

**Q: Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?**
A: The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Very Good. Not a "beginner strength" product. Prepare for prickling.
*by K***E on January 5, 2026*

If you're familiar at all with microneedling, this is the same idea. There are little spicy led (to y dissolving needles) in this serum that make micro channels in your skin to allow products to penetrate more deeply. It also has three gentle chemical exfoliants to smooth and brighten skin. It's a fairly thick, non-sticky serum, and it prickles quite a bit when you massage it in. I bought this on a whim and found out later that this is NOT "beginner strength". A starter serum would be a 100 ppm level. 2000 is definitely more intense and I do get some irritation immediately afterward. I own a professional grade microneedling machine, but between setting it up and sterilizing, it just feels like more of a project than I want to do for shallow, frequent needling. This serum is a nice shortcut and really, really speeds up the results I see from other products, and I use it roughly o CD a week.

### ⭐⭐⭐⭐⭐ Timeless beauty in a bottle
*by H***S on March 6, 2025*

I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉

### ⭐⭐⭐⭐⭐ My skin did a 180 overnight!
*by C***S on February 2, 2026*

I’m not usually one to write reviews, but this serum genuinely caught me off guard in the best way. I already love Medicube and have used several of their products, so I trusted the brand. What I did not expect was to see such a dramatic difference literally overnight. My skin did a complete 180, and it was obvious the second I looked in the mirror the next morning. What makes it even more surprising is that I am using the 2000X Exosome Shot. I honestly cannot believe the results were this noticeable with the lower strength. It makes me even more curious about the 7500 shot because if this is what 2000X can do, I can only imagine how much more intense the higher strength will be. I am genuinely excited to move up to it once I finish this bottle, which I absolutely will. After just one use, my skin looked smoother, brighter, and more even. The texture on my cheeks looked refined, redness appeared calmer, and there was this healthy, almost glassy glow that usually takes weeks of consistency to achieve. I actually paused and looked twice because I was not expecting to see visible changes that quickly. I’ve been using it as the second step in my routine to help the rest of my serums absorb better, and it completely changed how everything layers. The products I apply afterward seem to sink in more evenly and feel more effective overall. I also tried applying it before toner, and my skin responded beautifully either way. It really feels like it preps the skin so the rest of your routine can actually work the way it is supposed to. Of course, like any active product, it delivers the best results when it is used correctly and consistently. My skin has honestly not looked this good since I was a teenager (15+ years ago). That alone says everything. The improvement is visible, not subtle, and the overall quality of my skin just looks healthier and smoother. 100% worth it and for a fraction of the price for microneedling with just as great results. It truly exceeded my expectations. I cannot recommend it enough. If you have been debating whether to try it, take this as your sign to stop overthinking and just go for it.

## Frequently Bought Together

- medicube Zero Exosome Shot 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
- Medicube Zero Pore Pads 2.0, Dual-Textured Facial Toner Pads for Exfoliation and Pore Care with 4.5% AHA Lactic Acid & 0.45% BHA Salicylic Acid, Ideal for All Skin Types, Korean Skin Care (70 Pads)
- medicube Collagen Jelly Cream- Niacinamide & Freeze-Dried Hydrolyzed Collagen - Boosts skin's barrier hydration and gives 24h Glow & Lifted Look - No artificial color, Korean skincare (3.71 fl.oz.)

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-02-16*