---
product_id: 603060365
title: "K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply"
brand: "k9 advantix"
price: "FREE"
currency: JPY
in_stock: false
reviews_count: 5
category: "K9 Advantix"
url: https://www.desertcart.jp/products/603060365-k9-advantix-ii-large-dog-vet-recommended-flea-tick-mosquito
store_origin: JP
region: Japan
---

# Protects dogs 21-55 lbs Waterproof after 24 hours Kills fleas in 12 hours K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply

**Brand:** k9 advantix
**Price:** FREE
**Availability:** ❌ Out of Stock

## Summary

> 🐾 Stay ahead of pests—because your dog deserves the best defense!

## Quick Answers

- **What is this?** K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply by k9 advantix
- **How much does it cost?** FREE with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/603060365-k9-advantix-ii-large-dog-vet-recommended-flea-tick-mosquito)

## Best For

- k9 advantix enthusiasts

## Why This Product

- Trusted k9 advantix brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **No Prescription Hassle:** Available OTC so your dog stays protected without delays
- • **Rapid Flea Elimination:** Kills fleas within 12 hours to stop infestations fast
- • **All-in-One Pest Defense:** Vet-recommended formula repels & kills fleas, ticks, mosquitoes, biting flies, and lice
- • **Waterproof & Fragrance-Free:** Lasts through water exposure with no overpowering scent
- • **Effortless Monthly Protection:** Easy topical application—no pills or collars needed

## Overview

K9 Advantix II Large Dog is a vet-recommended, topical flea, tick, mosquito, biting fly, and lice treatment for dogs 21-55 lbs. It kills fleas within 12 hours, repels pests on contact, is waterproof after 24 hours, fragrance-free, and requires no prescription. Monthly use prevents infestations and protects your dog from pest-borne diseases with a quick, easy application.

## Description

K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.

Review: If you got flees, order this ! - I swear by this stuff , always works within 24 hours . Better than frontline and other flea medication.
Review: No more fleas - I have 2 dogs and buy the L and XL size. It works great for both of them. When I first moved into my rental house, I had a flea problem, but since using these and spraying in and around the house, it is under control. Definitely recommend.

## Features

- K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07NX5BJK8 |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | Adult |
| Best Sellers Rank | #72,023 in Pet Supplies ( See Top 100 in Pet Supplies ) #78 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.3 out of 5 stars 5,498 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089114938 |
| Item Form | Topical |
| Item Weight | 0.01 Ounces |
| Item form | Topical |
| Item volume | 2.5 Milliliters |
| Item weight | 0.01 Ounces |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 90204385 |
| Model Number | 90204385 |
| Pet Type | Dog |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089114938 |
| Unit Count | 1.0 Count |
| Volume | 2.5 Milliliters |

## Product Details

- **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen
- **Brand:** K9 Advantix
- **Item form:** Topical
- **Item weight:** 0.01 Ounces
- **Scent:** Unscented

## Images

![K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 1](https://m.media-amazon.com/images/I/71Ku9s2eqnL.jpg)
![K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 2](https://m.media-amazon.com/images/I/91Pj34vv7cL.jpg)
![K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 3](https://m.media-amazon.com/images/I/81lc7ZPFGHL.jpg)
![K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 4](https://m.media-amazon.com/images/I/81ffnFEbBPL.jpg)
![K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply - Image 5](https://m.media-amazon.com/images/I/71Bs7yQ8ocL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ If you got flees, order this !
*by D***E on 14 September 2026*

I swear by this stuff , always works within 24 hours . Better than frontline and other flea medication.

### ⭐⭐⭐⭐⭐ No more fleas
*by V***E on 19 August 2026*

I have 2 dogs and buy the L and XL size. It works great for both of them. When I first moved into my rental house, I had a flea problem, but since using these and spraying in and around the house, it is under control. Definitely recommend.

### ⭐⭐⭐⭐⭐ Works Great with my Goldendoodle!
*by K***E on 20 August 2026*

I love Advantix II. It works great for my Goldendoodle. The product always comes packaged properly and on time. He has never had any skin irritations from it and there is no offensive smell. If your dog is experiencing physical complications from using Advantix II, maybe he or she is allergic to one of the ingredients.

## Frequently Bought Together

- K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply
- K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 1-Mo Supply
- K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 1-Mo Supply

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-10-04*