--- product_id: 52352076 title: "SkinMedica Retinol Serum 0.25 Complex - Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles - 1 Fl Oz" brand: "skinmedica" price: "¥20911" currency: JPY in_stock: true reviews_count: 12 url: https://www.desertcart.jp/products/52352076-skinmedica-retinol-serum-0-25-complex-serum-for-face-age store_origin: JP region: Japan --- # 0.25% Retinol potency for gentle yet effective renewal Improves skin tone, texture & resiliency visibly Suitable for all skin types, including sensitive SkinMedica Retinol Serum 0.25 Complex - Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles - 1 Fl Oz **Brand:** skinmedica **Price:** ¥20911 **Availability:** ✅ In Stock ## Summary > ✨ Unlock timeless skin with every drop ⏳ ## Quick Answers - **What is this?** SkinMedica Retinol Serum 0.25 Complex - Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles - 1 Fl Oz by skinmedica - **How much does it cost?** ¥20911 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/52352076-skinmedica-retinol-serum-0-25-complex-serum-for-face-age) ## Best For - skinmedica enthusiasts ## Why This Product - Trusted skinmedica brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Radiance Renewed:** Enhances skin tone and texture for a youthful, glowing complexion. - • **Universal Skin Ally:** Gentle enough for all skin types, ensuring broad usability without irritation. - • **Pore & Acne Minimizer:** Helps reduce acne breakouts and visibly minimizes pores for smoother skin. - • **Age-Defying Powerhouse:** Clinically formulated 0.25% retinol to visibly reduce fine lines and wrinkles. - • **Youthful Resilience Boost:** Strengthens skin’s natural barrier to maintain elasticity and firmness. ## Overview SkinMedica Retinol Serum 0.25 Complex is a dermatologist-backed, age-defying serum designed to renew skin by diminishing fine lines, improving tone and texture, and minimizing pores. Suitable for all skin types, this advanced formula delivers gentle yet effective retinol benefits to keep your skin youthful, radiant, and resilient. ## Description Product Description Renews skin and diminishes the appearance of fine lines. Brand Story Improve the appearance of skin with effective formulas that help address the many factors that lead to premature aging. SkinMedica’s three varying strengths of retinols enhance skin’s radiance, tone, texture, and resiliency. ## Features - Suitable for all skin types - Renews skin and diminishes the appearance of fine lines - Greatly enhances skin tone, texture, and resiliency - Keeps the skin youthful - Helps in reducing acne breakouts and minimize the appearance of pores ## Technical Specifications | Specification | Value | |---------------|-------| | Asin | B00G193R40 | | Best Sellers Rank | #78 in Facial Peels | | Department | Beauty | | Item Model Number | 94917 | | Manufacturer | Skin Medica | | Product Dimensions | 1.75 x 5.65 x 1.75 inches; 2 ounces | | Upc | 367402315126 300234917014 300236515997 | ## Product Details - **Age Range (Description):** Adult - **Brand:** SkinMedica - **Item Volume:** 1 Fluid Ounces - **Item dimensions L x W x H:** 1.75 x 5.65 x 1.75 inches - **Special Feature:** Not-Applicable ## Images ![SkinMedica Retinol Serum 0.25 Complex - Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles - 1 Fl Oz - Image 1](https://m.media-amazon.com/images/I/51GSoFed3EL.jpg) ## Available Options This product comes in different **Set name** options. ## Questions & Answers **Q: Is this better than Neutrogenas rapid wrinkle relief line?** A: This and the SkinMedica Moisturizer are two of the best skin products I have ever used. Small lines have disappeared, my skin looks better than it ever has. Think I will up grade to the Retinol 0.50 Complex next. I tried the Neutrogena products - this is way better because it actually works! **Q: How many pumps does one bottle have? Or how long would one bottle last?** A: It lasts me about two months...I only use one pump per use. It is awesome stuff! Be sure to put moisturizer on top f it as it will dry your skin otherwise. I use their super moisturizer. Have used it for over a year...my skin has never looked better. **Q: Is .5 stronger than .25?** A: Yes. And the 1.0 is stronger than both. It is ideal to work up the progression scale if you have not used a Retinol before or it has been a long period of time between uses. Start with the .25 then move on to the .5 etc... **Q: How do I know which retinol % to use?** A: Use .25%. You are to use it daily. A pump at bedtime. If it is too strong you cannot use it nightly and it needs to be used nightly for effect. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Great product to be used at night *by on Reviewed in the United States July 2, 2026* Great product. Make sure to use it at night only as it is not to be used in the sun. My skin is glowing and looks beautiful. ### ⭐⭐⭐⭐⭐ Great product. Don't think it twice to get it. *by on Reviewed in the United States March 16, 2026* I was using the .5 and started with the 1.0 just a week ago. I can see the difference in just one week. I have mix skin with acne scars and sun marks. Skin got softly peeled and already got a firmer and smoother look. I highly recommend but judging for it's immediate action I would say to take breaks for sensitive skins in between usage. For the rest this product is high quality. Highly recommended. ### ⭐⭐⭐⭐⭐ Effective retinol with no prescription *by on Reviewed in the United States May 10, 2026* I’ve been using SkinMedica Retinol 1.0 for several months and the results are impressive. This is definitely the best retinol you can buy without prescription. Best for people who already have experience with retinoids, not recommended for beginners . The first days I had some redness and flaking, which is normal for a 1.0% retinol. After few weeks of using my skin looked much smoother, pores appeared smaller, and my overall tone became more even. I use it only at night with a rich moisturizer. You must use sunscreen daily ## Frequently Bought Together - SkinMedica Retinol 0.25 Complex - Retinol Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles, 1 Fl Oz - SkinMedica Vitamin C+E Complex - Vitamin C Face Serum is Your Secret to a Glowing Complexion --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.jp/products/52352076-skinmedica-retinol-serum-0-25-complex-serum-for-face-age](https://www.desertcart.jp/products/52352076-skinmedica-retinol-serum-0-25-complex-serum-for-face-age) --- *Product available on Desertcart Japan* *Store origin: JP* *Last updated: 2026-08-16*