--- product_id: 477082447 title: "Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose" brand: "advantage" price: "¥11572" currency: JPY in_stock: true reviews_count: 8 category: "Advantage" url: https://www.desertcart.jp/products/477082447-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats store_origin: JP region: Japan --- # 2 months protection per dose Kills fleas within 30 min to 4 hrs Award-winning natural Spinetoram Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose **Brand:** advantage **Price:** ¥11572 **Availability:** ✅ In Stock ## Summary > 🐾 Keep your cat flea-free and fabulous for 8 weeks straight! ## Quick Answers - **What is this?** Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose by advantage - **How much does it cost?** ¥11572 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/477082447-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats) ## Best For - advantage enthusiasts ## Why This Product - Trusted advantage brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Rapid Relief:** Starts killing fleas within 30 minutes, stopping bites before they happen - • **Eco-Chic Formula:** Fragrance-free, naturally derived Spinetoram with a prestigious Green Chemistry Award - • **Double the Defense:** 2 months of continuous flea protection—twice as long as typical treatments - • **Vet-Recommended & OTC:** Trusted by professionals and available without prescription for ultimate convenience - • **Effortless Application:** Topical spot-on treatment applied in seconds—no pills, no hassle ## Overview Advantage XD Large Cat Flea Prevention delivers a powerful, 2-month topical treatment for cats over 9 lbs and 8 weeks old. Featuring fast-acting Spinetoram, it kills fleas within hours and prevents reinfestation longer than standard 1-month options. This fragrance-free, award-winning formula is easy to apply, safe for indoor and outdoor cats, and available over the counter—perfect for busy cat parents who demand effective, eco-conscious care. ## Description "Cat lovers choose Advantage XD for double the lasting protection against fleas vs. other 1-month options. Advantage XD for large cats and kittens packs two full months of treatment and continuous protection in each dose, so your cat is protected for longer than the traditional 1-month formula.* If your cat has already tousled with fleas, you’ll love that Advantage XD topical treatment starts killing fleas within 30 minutes to 4 hours through contact so they don’t have to bite and die. And with Advantage XD extended duration formula, that flea prevention remains effective for 8 weeks, outlasting the typical 6-week flea life cycle and preventing reinfestation.Find Advantage XD topical flea treatment available in a variety of pack sizes, from 2 months protection (1 dose), to 4 months protection (2 doses), or 8 months protection (4 doses). This fragrance-free formula contains Spinetoram, a naturally derived, Green Chemistry Award-winning** ingredient.Advantage XD flea infestation prevention is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and weigh over 9 lbs. to use Advantage XD for large cats. Even with the squirmiest of kittens and cats, application is easy. The single, topical, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It's easier, there are no hard-to-swallow pills; this topical treatment goes on in seconds. See product label for more information.For the ultimate convenience in care, Advantage XD is available over the counter – no prescription needed. Once Advantage XD is applied, your cat is ready to get right back to exploring the outdoors or finding a cozy spot for a nap, while you get to enjoy peace of mind.*Based on label claims **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008. " Review: Good product - Good price for flea control. Review: Cat flea medication - This product’s always works. Never had an issue with it or always buy this product. ## Features - 2 months (1 dose) flea treatment and prevention for indoor and outdoor cats and kittens over 9 lbs., 8 weeks or older - Longer-lasting protection vs. other topical products;* 2 months protection per dose, outlasting the typical flea life cycle *Based on label claims - Fast-acting treatment starts killing fleas within 30 minutes to 4 hours through contact - Easy-to-apply topical treatment, no prescription needed - Fragrance-free formula, containing a naturally derived ingredient Spinetoram - winner of a Green Chemistry award** **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0BCX9NJS1 | | Active Ingredients | Spinetoram | | Age Range Description | 8 weeks and older | | Allergen Information | Allergen-Free | | Best Sellers Rank | #2,810 in Pet Supplies ( See Top 100 in Pet Supplies ) #16 in Cat Flea Drops | | Brand | Advantage | | Brand Name | Advantage | | Customer Reviews | 4.4 out of 5 stars 4,434 Reviews | | Dog Breed Size | Large | | Global Trade Identification Number | 00727804566425 | | Item Form | Topical | | Item Type Name | Topical | | Item Volume | 2 Milliliters | | Item Weight | 0.04 Pounds | | Manufacturer | Elanco US Inc | | Manufacturer Part Number | CA4242006AM | | Model Number | CA4242006AM | | Scent | Unscented | | Scent Name | Unscented | | Target Species | Cat | | UPC | 727804566425 | | Unit Count | 1 Count | | Volume | 2 Milliliters | ## Product Details - **Active Ingredients:** Spinetoram - **Age Range (Description):** 8 weeks and older - **Allergen Information:** Allergen-Free - **Brand:** Advantage - **Dog Breed Size:** Large - **Item Form:** Topical - **Item Volume:** 2 Milliliters - **Item Weight:** 0.04 Pounds - **Scent:** Unscented - **UPC:** 727804566425 ## Images ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - Image 1](https://m.media-amazon.com/images/I/71eCyIacFPL.jpg) ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - Image 2](https://m.media-amazon.com/images/I/91yerRUCErL.jpg) ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - Image 3](https://m.media-amazon.com/images/I/81oJVGU7QtL.jpg) ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - Image 4](https://m.media-amazon.com/images/I/81pHA7gk1oL.jpg) ![Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - Image 5](https://m.media-amazon.com/images/I/81RYBHhrhyL.jpg) ## Available Options This product comes in different **Size, Style** options. ## Questions & Answers **Q: If this flea product is just microbes why are there the same warmings about poisoning and ingestion as Advantage2 ?** A: IT CAUSED THE FERAL CAT I TAKE CARE OF HAIR TO FALL OUT ONE DAY AFTER APPLICATION HE IS VERY STRONG SO DECIDED NOT TO USE ON MY RESCUE CAT WHO WAY SMALLER HONESTLEY I FEEL ITS JUST AS DANGEROUS GOOD LUCK **Q: Does this kill ear mites** A: No. Mites are related to spiders & harder to kill. Revolution does both. Or get specific ear mite meds **Q: How do you remove the cap?** A: It doesn't have a cap. You just twist the top the way it shows on the side of the tube. I think it's counter clockwise. **Q: Is the only difference between this and Advantage II the time it works fit** A: Hi. Advantage™ XD for cats starts killing fleas in 30 minutes to 4 hours. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Good product *by P***S on May 6, 2026* Good price for flea control. ### ⭐⭐⭐⭐⭐ Cat flea medication *by C***E on April 18, 2026* This product’s always works. Never had an issue with it or always buy this product. ### ⭐⭐⭐⭐⭐ So far so good *by T***N on August 18, 2023* FINALLY, my kittens and I have relief!! My new kittens came with unwanted guests but they were too young for the products I saw. I used a flea comb and baths with no real relief. Things got worse. I had my house and garage (where they're staying due to tenants allergies) fumigated before the fleas took hold of my house like they had the garage. I gave them both capstar while we waited. That evening I applied Frontline plus. They were still scratching. I gave another dose of capstar two days later hoping that they would finally be rid of all stages of fleas. NOPE. I gave the third dose. NOPE. Capstar works great but it only works on adult fleas for a short time. Frontline was useless. I finally applied advantage xd and finally we all have relief. No more incessant scratching. I truly hope it lasts. My kittens and I are so very grateful. I absolutely recommend this product. Don't waste money on Frontline plus. FYI, the tubes doesn't have a cap. The tops look like caps to be removed but it's the tip of the applicator. Just twist the top slightly and it's open. Nothing has to be removed. I needed YouTube to figure that out. ## Frequently Bought Together - Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose - K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply - K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 2-Mo Supply (Packaging may vary) --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.jp/products/477082447-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats](https://www.desertcart.jp/products/477082447-advantage-xd-large-cat-flea-prevention-and-treatment-for-cats) --- *Product available on Desertcart Japan* *Store origin: JP* *Last updated: 2026-05-21*