Advantage II XL Dog Topical Flea Treatment & Prevention, 6ct

Love that it’s safe for pregnant dogs and small puppies. We use the product on all our dogs and bought the cat version for our cats. No problems with fleas. Easily applied.

I've been using Advantage for flea control for several years, and Amazon is one of the best places to get it. You can't beat $10 a month for large dog flea protection. I also use one tube split into fifths (via syringe measurement) to give to my cats. Advantage II specifically is exactly the same product, in different dosages, for both dogs and cats. My 70-lb Lab gets a full 40 ml tube by herself, then the cats get 8 ml each and my brother-in-law's two ferrets get 4 ml each. I can cover 7 pets for $20 a month- a fantastic deal. The Advantage makes a noticeable difference in my pets' comfort- towards the end of the month, when it's wearing off, they begin to get itchy and uncomfortable. Once I reapply, that stops within a day or two, and they're happy and flea-free again all month. I have noticed that if our dog regularly gets into water (pool, beach, sprinklers), the Advantage wears off much quicker, despite claiming to be waterproof. That's understandable in a topical treatment, so we try to keep her out of water until the end of the application cycle, before a new treatment- then she gets to get wet to her heart's content! If you need to bathe your dog to kill fleas before applying, be sure to wait a day or two after the bath to give your dog's natural skin oils a chance to bounce back- it helps to distribute the medication. Be aware: this product is alcohol-based, and will evaporate quickly if left out in open air (we use a glass baby food jar to split the dosages in the syringe). It has also stripped the lacquer off the dining table when a few drops spilled while splitting doses, so try to avoid that too! Other than that, Advantage II is, in my opinion, the best topical flea control.

​Finding an effective flea treatment for a large dog can be a challenge, but Advantage II has always been my go-to. This 4-month supply for dogs 55+ lbs is perfect for keeping my dog protected throughout the season. It’s easy to apply, waterproof, and I love that it kills fleas at all life stages—larvae and eggs included—so we don't have to deal with any re-infestations. My order was delivered right on time on May 8th, and it's such a relief to have peace of mind knowing he's covered. Highly recommend for any large breed owners!

I have used this product for years on my dogs & can normally go as long as up to 8 weeks between doses. I have noticed that on some years (2014 & 2011) that the fleas are particular difficult to control. I know it is not due to this product not being effective because I have treated my yard with 2 different products that normally work very well within a 10 day period & even those products have made very little difference in the fleas. I have treated my dogs at 9 days & repeated again at 13 days. I am also using natural flea shampoo & topical sprays with essential oils. The fleas do die within 12 hours, but by that time my dog with allergies is a mess due to bites before they die. I am now seeing primarily very tiny fleas which tells me that I am achieving some control over the adult fleas. I dislike giving doses that close together, but that is what the insert recommends (actually every 7 days until controlled) for heavy flea infestations. One of my dogs has terrible flea allergies. He has been miserable & has been on prednisone & benadryl for over a month. I don't even like for him to be outdoors because they are so bad. I have to pick fleas off both dogs every time they step outside. I don't have any carpet in my home so I know they are not living in my house. It just seems that some years the fleas are just almost impossible to control. I am in Savannah, Ga. Last summer, the fleas were no problem at all. I did not even treat my lawn. I only gave Advantage every 6-8 weeks. The summer of 2011 was also a bad flea year. I'm not sure what is the cause, probably something to do with the weather or maybe they just have cyclic bad years (who knows). I thought this would be a mild year for fleas because the winter was so cold, but that apparently is not true. I have learned that unfortunately on bad flea years it will take a few months to get the fleas under control even using multiple products. Nothing much else you can do, but suffer until they are under control!!...............Update: After treating my yard with 2 different products within a month & treating my dogs with 3 doses (once every 10 days), the fleas appear to finally be under control. No fleas for 3 days!!! Allergic dog is finally getting some relief. Hopefully, I can now only treat my dogs monthly since I have gotten the severe flea infestation under control. It just takes a while to break the flea life cycle if you have a severe infestation..............UPDATE...Fleas are finally under control. Have not had to re-apply for 4 weeks. Just had a small flea on my allergic dog. Will re-apply today. Once you break the flea life cycle this will control the fleas. I buy the large dog size package & draw out the dosage for each dog with a blunt tip syringe. This is more cost effective & I have found that I can control the fleas by using a smaller dosage for my 30lb dog with allergies. The size package for his weight is a 2.5ml dose (weight range 21-55 lbs). He only weighs 30lbs & the weight limit is a very broad range for his size. The next smaller size range (10 to 20 lbs) is 1.0 ml so at approximately 0.5ml per 10 lbs, I don't feel he needs the entire 2.5ml dose & I have found that he does not. I normally am able to give him only 1.5 to 2.0 ml which will work fine once the severe infestation is under control. I don't like having to give chemicals to my dog & the less the better. He also has skin problems & the Advantage does seem to flare up his skin problems, so less is better. I am also able to give my cat a dose if he happens to pick up an untreated flea (he is an inside cat, but he will occasionally sneak out if he can). The Advantage is the same ingredients for dogs & cats (also confirmed with my vet), but the Advantix is NOT. DO NOT give Advantix to cats!

I've used this for many years and it does the job

Works for 30 days without entering your dogs blood stream. It stays in the fatty tissue. THEREFORE NOT TAXING YOUR DOGS VITAL ORGANS.

I've been using this for years. It works pretty good. It's becoming less and less effective as the fleas evolve to it. But right now it's still pretty effective.

I live in the American South, and my vets agree that Advantage works better than Frontline or any generic products. To get the most value for your money, I recommend buying the dosage for extra-large dogs and splitting it among smaller dogs. Save a small jar such as for pimentos or olives. Ask your pharmacist for a plastic dosing syringe (the kind for giving kids liquid medicine); they will likely give you one. I've attached a sample picture of the type of syringe you need. You need one without a needle that holds the amount of ML you will be using, based on the below guidelines. Take off your dog's collar to ensure it doesn't slide down onto where you will be putting the Advantage. Open a package of Advantage and pour it into the jar. Pull into the syringe the right amount for your dog's weight: 0.4ml = 0-10# 0.8ml = 11-20# 1.2ml = 21-30# 1.6ml = 31-40# 2.0ml = 41-50# 2.4ml = 51-60# 2.8ml = 61-70# 3.2ml = 71-80# You will put part of the Advantage on the dog's neck, and part of it in a few places down his back. Use your fingers to part the dog's hair on the back of his neck. (See package instructions on where to place the treatment.) Slowly depress the plunger onto the skin, NOT on top of the hair. Otherwise, it will drip off of the hair. Do several more spots down the dog's spine. Immediately give treats to keep them from shaking their heads around. I learned the hard way that, if your dog vigorously shakes, this product can take the paint off cabinets and the varnish off stainless steel!! I do the treatment outside and leave the dogs outside for an hour or so. Buying the largest size of Advantage and dosing several dogs with it can save a lot of money in the long run. Let's say your dog weighs 32 lbs, and you purchase the "Large dog for pets 21-55 lbs" and put the entire tube on him. You will be giving him 2.5 ML when he really only needs 1.6 ML. In a home with several dogs, this can add up! Of course, talk to your vet if you have questions. This is just how I do it at my house! I am not a vet. I plan to post a video showing how I use this method. **I have relied heavily on reviews for years, since I do most of my shopping online. I've finally starting trying to return the favor by writing reviews of products I love. I hope my review was helpful to you!**