---
product_id: 430327437
title: "SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules)"
brand: "designs for health"
price: "¥25925"
currency: JPY
in_stock: true
category: "Designs For Health"
url: https://www.desertcart.jp/products/430327437-same-capsules-with-b6-b12-5-mthf-200mg-s-adenosylmethionine
store_origin: JP
region: Japan
---

# Patented tech for max absorption 200mg SAMe for brain & mood boost Immune & cell membrane support SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules)

**Brand:** designs for health
**Price:** ¥25925
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your mind & immunity with science-backed SAMe!

## Quick Answers

- **What is this?** SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) by designs for health
- **How much does it cost?** ¥25925 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/430327437-same-capsules-with-b6-b12-5-mthf-200mg-s-adenosylmethionine)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Trusted Formula:** Non-GMO, gluten-free, vegetarian, and physician-preferred since 1989
- • **Immune & Cellular Shield:** Strengthens immune system and protects cell membranes
- • **Complete Cofactor Complex:** Includes B6, B12 & 5-MTHF for efficient SAMe metabolism
- • **Optimized Absorption Tech:** Patented stabilized powder ensures SAMe survives stomach acid intact
- • **Neurotransmitter Powerhouse:** Supports serotonin & melatonin for mood & restful sleep

## Overview

Designs for Health SAMe Capsules deliver 200mg of stabilized S-Adenosylmethionine combined with essential cofactors B6, B12, and 5-MTHF folate. This advanced formula supports neurotransmitter synthesis, immune function, and cellular health with patented technology ensuring superior absorption. Non-GMO, gluten-free, and vegetarian-friendly, it’s a professional-grade supplement trusted by over 50,000 doctors since 1989.

## Description

SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors B12 and folate. SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage. These capsules provide 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF in order to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. Made with non-GMO ingredients.

## Features

- Immune And Hormone Support - S-Adenosylmethionine or SAMe is a naturally occurring compound found in the human body as well as in plant and animal foods. It is involved in many processes throughout the body. SAMe plays a role in supporting the immune system and maintaining cell membranes, the protective barrier that surrounds all cells. It also helps to produce neurotransmitters like melatonin- that helps with your body's rest cycle, and serotonin, the "feel good" hormone. *
- Includes Necessary Cofactors - Each capsule provides 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. *
- Special Technology - Our SAMe capsules are made using special technology with a patented stabilized powder which protects the SAMe from being destroyed by air and moisture. This cutting-edge technology prevents its breakdown by stomach acidity and allows the capsule to be absorbed intact in the small intestine. *
- Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy.*
- Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00B9EF6KA |
| ASIN  | B00B9EF6KA |
| Age Range Description | Adult |
| Best Sellers Rank | #201,894 in Health ( See Top 100 in Health ) #1,492 in Vitamin B Supplements |
| Brand Name | Designs for Health |
| Customer Reviews | 4.6 4.6 out of 5 stars (102) |
| Customer reviews | 4.6 4.6 out of 5 stars (102) |
| Diet Type | Gluten Free, Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00879452003781 |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions | 5.7 x 7.6 x 10.2 centimeters |
| Item Form | Capsule |
| Item model number  | SAM030 |
| Manufacturer | Designs for Health |
| Manufacturer  | Designs for Health |
| Manufacturer Part Number | SAM030 |
| Material Features | Gluten Free |
| Material Type Free | Dairy Free, GMO Free, Soy Free |
| Model Name | Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) |
| Model Number | SAM030 |
| Number of Items | 1 |
| Primary Supplement Type | Vitamin-b |
| Product Benefits | Brain Health Support |
| Product Dimensions  | 5.72 x 7.62 x 10.16 cm; 118 g |
| Special Ingredients | Gluten Free |
| Specific Uses For Product | Immune,Immune System |
| Total Servings Per Container | 30 |
| UPC | 879452003781 |
| Unit Count | 30 Count |

## Product Details

- **Age range (description):** Adult
- **Brand:** Designs for Health
- **Diet type:** Gluten Free, Vegetarian
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 5.7 x 7.6 x 10.2 centimeters
- **Item form:** Capsule
- **Primary supplement type:** Vitamin-b
- **Product benefits:** Brain Health Support
- **Special ingredients:** Gluten Free
- **Unit count:** 30 Count

## Images

![SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 1](https://m.media-amazon.com/images/I/71obsWgSkUL.jpg)

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-08-23*