---
product_id: 3999955
title: "Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe), 30 Tablets"
brand: "nutramax laboratories"
price: "¥11312"
currency: JPY
in_stock: true
reviews_count: 8
category: "Nutramax Laboratories"
url: https://www.desertcart.jp/products/3999955-nutramax-denosyl-liver-and-brain-health-supplement-for-medium-dogs
store_origin: JP
region: Japan
---

# Proven bioavailability for fast bloodstream absorption Neuroprotective benefits to boost cognitive sharpness 225mg SAMe for potent liver & brain support Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe), 30 Tablets

**Brand:** nutramax laboratories
**Price:** ¥11312
**Availability:** ✅ In Stock

## Summary

> 🐾 Elevate your dog’s vitality — because sharp minds and healthy livers never go out of style!

## Quick Answers

- **What is this?** Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe), 30 Tablets by nutramax laboratories
- **How much does it cost?** ¥11312 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/3999955-nutramax-denosyl-liver-and-brain-health-supplement-for-medium-dogs)

## Best For

- nutramax laboratories enthusiasts

## Why This Product

- Trusted nutramax laboratories brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Dual-Action Support:** Simultaneously enhances liver antioxidant glutathione and cognitive function
- • **Vet-Trusted Formula:** From the #1 veterinarian recommended supplement brand with 30+ years of expertise
- • **Easy-to-Administer Tablets:** Enteric-coated for optimal absorption and gentle on your dog’s stomach
- • **Clinically Potent SAMe Dose:** 225mg of bioavailable S-Adenosylmethionine powers liver detox & brain health
- • **Proven Customer Satisfaction:** 4.6-star rating from over 1,000 pet parents who see real results

## Overview

Nutramax Denosyl delivers 225mg of bioavailable S-Adenosylmethionine (SAMe) per tablet, scientifically formulated to support medium dogs’ liver health by boosting glutathione levels and promoting cognitive function. Trusted by veterinarians for over 30 years, this enteric-coated supplement ensures effective absorption and gentle digestion, backed by a 4.6-star rating from more than 1,000 satisfied customers.

## Description

Denosyl contains SAMe (s-adenosylmethionine) to help support the liver health of dogs and may support brain health. It is available in enteric-coated tablets. Denosyl Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.

Review: Please buy this for your dog! Great for Cognitive issues and liver! - Currently waiting on 2 more packs of these! I ran out 2 days ago and my girl is getting anxious again. She has slightly elevated liver enzymes but I started her on this for cognitive issues. She is still listening to commands and doesn't get lost but her night time anxiety and barking has increased now that she is almost 11. This girl has been through everything medically. Her bloodwork, urine and stool samples are all flawless other than the slight elevated liver levels. We have been fighting symptoms for 2 months and THIS supplement got her back to 100%. She is seriously so sharp now! I will keep her on these for life. Just seeing what day 2 without them is like. She's not bad, but her normal routine is being disturbed by her barking and pacing. It should be here within an hour. I almost guarantee she will be back to normal by tomorrow. I gave her all her meds (even extra cbd). The only thing she has missed is this med and she is more irritable/anxious. I seriously can't wait to get these in. I give them afternoon after we get home from work, on an empty stomach and 2 hours before dinner. She is on a probiotic and pumpkin, so no stomach upset. Put it in a pill pocket if they wont take it! Once it started helping her, she takes it with no problem. She wants to take it! Thank you for making a supplement that WORKS!
Review: Great price - Cheaper here then from the Vet, my pup takes these daily

## Features

- Liver Support: Denosyl features s-adenosylmethionine (SAMe) to support the liver by increasing levels of glutathione, an important antioxidant for liver health and the liver's main detoxifier
- Bioavailability: The SAMe in Denosyl has been proven to be bioavailable, meaning it enters your pet's bloodstream to help support the liver
- Cognitive Support: Research has shown that SAMe may also support cognitive function in dogs and act as a neuroprotector
- From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Active Ingredients | S-Adenosylmethionine 225 mg |
| Brand | Nutramax Laboratories |
| Customer Reviews | 4.6 out of 5 stars 1,089 Reviews |
| Dog Breed Size | Medium |
| Item Form | Tablet |
| Item Weight | 0.02 Pounds |
| Product Benefits | Antioxidant |

## Product Details

- **Active Ingredients:** S-Adenosylmethionine 225 mg
- **Brand:** Nutramax Laboratories
- **Item Form:** Tablet
- **Item Weight:** 0.02 Pounds
- **Product Benefits:** Antioxidant

## Images

![Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe), 30 Tablets - Image 1](https://m.media-amazon.com/images/I/61nX1rMLOPL.jpg)

## Available Options

This product comes in different **Size, Item Package Quantity** options.

## Questions & Answers

**Q: Is Denosyl vegan?**
A: We gave it to are dachshund for liver help.Worked  very well price.was better then at vet. When I ask ask her if she was vegan she said she wanted to feel better and that it did.so are you asking for you or your pet?

**Q: What is the difference between this and denamarin? my chihuahua is taking denamarin to improve liver function. would this do the same thing?**
A: My dog had complete liver failure so Denamarin was prescribed since it provides stronger liver support. They both contain the same main ingredient, but Denamarin also contains a form of milk thistle.  I had a bad experience with Denosyl(my dog started vomiting black liquid, but I don't know if it was just a coincidence that he got sick the same day he took the Denosyl and I didn't want to risk it) Always consult your vet before switching or starting medications, and if your are going to buy online make sure it is a reputable company.  After my incident I only purchase Denamarin from my vet even though it costs a lot more.

**Q: Do you need a script from vet to order?**
A: This does not require a prescription from a vet

**Q: How does this compare to denamarin?**
A: The central difference between the two medications is a second ingredient that is found in Denamarin but not Denosyl. This ingredient, silyb in, provides additional liver support and can work in conjunction with SAM-e to promote healthy liver function. This means that Denamarin is a stronger supplement for pets that need maximum liver support.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Please buy this for your dog! Great for Cognitive issues and liver!
*by A***R on December 28, 2025*

Currently waiting on 2 more packs of these! I ran out 2 days ago and my girl is getting anxious again. She has slightly elevated liver enzymes but I started her on this for cognitive issues. She is still listening to commands and doesn't get lost but her night time anxiety and barking has increased now that she is almost 11. This girl has been through everything medically. Her bloodwork, urine and stool samples are all flawless other than the slight elevated liver levels. We have been fighting symptoms for 2 months and THIS supplement got her back to 100%. She is seriously so sharp now! I will keep her on these for life. Just seeing what day 2 without them is like. She's not bad, but her normal routine is being disturbed by her barking and pacing. It should be here within an hour. I almost guarantee she will be back to normal by tomorrow. I gave her all her meds (even extra cbd). The only thing she has missed is this med and she is more irritable/anxious. I seriously can't wait to get these in. I give them afternoon after we get home from work, on an empty stomach and 2 hours before dinner. She is on a probiotic and pumpkin, so no stomach upset. Put it in a pill pocket if they wont take it! Once it started helping her, she takes it with no problem. She wants to take it! Thank you for making a supplement that WORKS!

### ⭐⭐⭐⭐⭐ Great price
*by J***Y on July 8, 2025*

Cheaper here then from the Vet, my pup takes these daily

### ⭐⭐⭐⭐⭐ If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl ...
*by J***N on December 26, 2016*

I have a 12 year old Siberian Husky. Ever since she was about 6 years old, I have had a full blood panel run on her once a year. This past June for the first time ever she had a slightly elevated liver level. It was 198. The year before it was 155. The vet wasn't too concerned as it was only slightly elevated. He said that I could start giving her Denosyl. The price at the vet was $85.00 for 30 pills. I fount it here on Amazon for $50. I started giving it to here in July or August. I have been giving it to for about 4 months. I probably give it to her about 4 days a week. Since her levels were only slightly elevated I figured it was okay if I missed a few days a week. I also give her Metacam daily for arthritis that she has had since she was a puppy. I have 4 Siberian Huskies and it obviously gets expensive caring for all of them, so it saves a little money not giving it to her everyday. I took her this week to have another blood panel run. It has been 6 months since the last blood work in June 2016. Her Liver level dropped from 198 to 142! It is now lower than it was a year and half ago when I tested her in June 2015 and it was 155 and was still considered normal. I am thrilled with the results of this in only 4 months giving it to her everyother day. If her levels had been higher I would have given it to her every day like recommended. The vet told me that the Denosyl must be working and that I can still give it to her everyother day if I would like. I will definitely continue giving this product to my dog. I am thrilled with the results in just 4 short months.

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-02-05*