---
product_id: 358554570
title: "Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets"
brand: "life extension"
price: "¥9185"
currency: JPY
in_stock: true
reviews_count: 5
category: "Life Extension"
url: https://www.desertcart.jp/products/358554570-life-extension-optimized-folate-l-methylfolate-1700-mcg-dfe-180
store_origin: JP
region: Japan
---

# 180 vegetarian, non-GMO tablets 1700 mcg bioactive 5-MTHF folate crosses blood-brain barrier for cognitive support Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets

**Brand:** life extension
**Price:** ¥9185
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your wellness game with the folate that’s already winning the bioavailability race!

## Quick Answers

- **What is this?** Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets by life extension
- **How much does it cost?** ¥9185 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/358554570-life-extension-optimized-folate-l-methylfolate-1700-mcg-dfe-180)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Long-Lasting Supply:** 180 tablets per bottle—designed to keep you optimized for 6 months of daily wellness.
- • **Brain & Heart Synergy:** Supports neurotransmitter synthesis and healthy homocysteine levels to boost cognitive and cardiovascular health.
- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegetarian tablets crafted with premium ingredients in the USA.
- • **Trusted Quality Assurance:** Every batch comes with a Certificate of Analysis ensuring purity and potency you can rely on.
- • **Bioactive Folate Powerhouse:** 1700 mcg of 5-MTHF, the metabolically active form, for superior absorption and efficacy.

## Overview

Life Extension Optimized Folate delivers 1700 mcg of 5-MTHF, the active form of folate, in 180 vegetarian, non-GMO tablets. This supplement supports cardiovascular and cognitive health by promoting neurotransmitter synthesis and maintaining healthy homocysteine levels. Manufactured in the USA with premium ingredients and backed by rigorous quality testing, it offers a potent, bioavailable alternative to traditional folic acid supplements.

## Description

Life-Extension Optimized Folate, 180 Vegetarian Tablets A Folic Acid / B9 Vitamin Supplement Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. Why Choose Life Extension's Optimized Folate? ✔ More bioavailable than folic acid ✔ Non-GMO ✔ Vegetarian tablets Unlike other brands that use folic acid, Life Extension's Folate is made from 5-Methyltetrahydrofolate because it is more bioactive. Health benefits ◆ Supports neurotransmitter synthesis ◆ Helps maintain healthy homocysteine levels already within the normal range. Unlike folic acid, Life Extension 5-MTHF (in this Optimized Folate supplement) is able to cross the blood-brain barrier. Choose Life Extention's Optimized Folate because it is already in the bioactive state, unlike traditional folate. Add to your cart because you deserve the best folate supplement.

Review: I like the dosage, the price, and the quality.
Review: I switched from 10X due to availability a few months ago and am really satisfied.

## Features

- Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Vegetarian Tablets
- Life Extension's Optimized Folate formula promotes both cardiovascular and cognitive health with 1,700 mcg of folate in the form of 5-MTHF, the metabolically active form of folic acid.
- Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
- Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07LB63PFJ |
| ASIN  | B07LB63PFJ |
| Age Range Description | Adult |
| Best Sellers Rank | #124,573 in Health ( See Top 100 in Health ) #1,120 in Vitamin B Supplements |
| Brand | Life Extension |
| Customer Reviews | 4.7 4.7 out of 5 stars (2,905) |
| Customer reviews | 4.7 4.7 out of 5 stars (2,905) |
| Date First Available | 16 April 2019 |
| Format | Bar |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | Life Extension |
| Manufacturer reference  | 01939 |
| Package Dimensions  | 11 x 4.6 x 4.5 cm; 68 g |
| Serving Recommendation | 1 tablet |
| Units | 180.0 Count |

## Product Details

- **Brand:** Life Extension
- **Diet type:** Vegetarian
- **Flavour:** Unflavored
- **Item form:** Bar
- **Primary supplement type:** Folate

## Images

![Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets - Image 1](https://m.media-amazon.com/images/I/61A3AMT1ylL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by T***G on 19 January 2025*

I like the dosage, the price, and the quality.

### ⭐⭐⭐⭐⭐ Review
*by D***Y on 3 July 2025*

I switched from 10X due to availability a few months ago and am really satisfied.

### ⭐⭐⭐⭐⭐ Review
*by C***Y on 29 June 2017*

I started taking this product after seeing my genetic results indicate that I am unable to process Folic Acid into Methylfolate (90% reduction) I started taking it with no expectations, but the results were very clear. I felt calmer the next day, (ADHD) I didn't feel tired and no longer wanted to take a nap after work every day. My impulse control was much better while taking. Depressive thoughts or rumination were greatly reduced. There are side effects for me though: An hour to three after taking, I noticed increased agression or manic thoughts. It's somewhat subtle, and has not caused any issues, but it's there. The next day, if I take a whole pill, under my eyes get very black. More so than any other "tired" look I've noticed before. This is why I don't take it regularly. It truly is a wonder pill for me, but I can't help thinking about the toll it takes on my body which perhaps I need to supplement it with the B12 as others indicate to avoid the side effects. Overall I'd recommend trying this.

## Frequently Bought Together

- Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets
- Life Extension BioActive Complete B-Complex, Heart, Brain and Nerve Support, Healthy Energy, Metabolism, Complete B Complex, 60 Vegetarian Capsules
- Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-01-26*