NATURDAO® DAO enzyme 1,000,000 HDU per tablet - DAO Enzyme Supplement - Histamine Block - Diamine Oxidase - Food Intolerance - 60 Extended Release Tablets

These work but they are stronger than I need. I take them 5 to 10 minutes before I eat. If I take them earlier than that, they make me feel icky. I cut them in 3's and only take before meals that have known histamine reactions. They work wonders for HI reactions. I recommend them to others.

NatruDAO is amazing! I've been feeling so tired and I have two other autoimmune conditions that I couldn't seem to get under control no matter what I did with diet, exercise, medications, supplements. Someone suggested that I may have a histamine intolerance so I read up on it and realized I have all the symptoms so I went looking for a DAO Supplement and although this product only had 56 reviews at the time I purchased it, every review had 5-stars. I read through the reviews since I'm skeptical when something has an abundance of 5-stars reviews but they all seemed to be from real people, so I ordered this product two weeks ago. It comes in a box of 60 tablets and you take one tablet 5 minutes before you have a meal, so you will probably use 2-4 a day depending on your eating habits. Some people have said they break the tablets in half so they get more value for their money. I haven't tried that yet. While this product may seem a bit on the pricey side, it is WELL worth the money. I noticed a huge difference the first day I took it. I started feeling less fatigued and had more motivation within the first 24 hours. After two weeks, I've noticed I'm not as bloated. I sleep better. My skin isn't as dry. My joints have been hurting less. My bowel function is almost back to normal. I brain feels less dizzy and my memory function that was starting to wane is improved. I've gotten more done around the house in the past two weeks than I have in the past four months because I haven't worked all day and then just felt like I needed a nap or that I was in too much pain to do anything. My spouse has commented that I have been in a much better mood and much less irritable. I haven't tried any other DAO supplements, so I don't know if any are comparable, but after using this product with such stellar results, I don't think I would change products unless another one had effects that were just as good but at a lower price. They also suggest eating a low histamine diet for additional support. I haven't gotten that far yet and have been eating regular foods, some high in histamine. I do plan to try low histamine foods as a means to feel even better, but this product seems to work well even when you're eating high histamine foods. Some high histamine foods I've eaten in the past two weeks while using this product include tomato sauce, shrimp, chocolate, egg whites, green peppers, pizza, cake made with wheat flour, ham, sausage, several oranges and orange juice. I know that my review makes this seem like a "miracle supplement" but if you have histamine intolerance, it really is. Now that I have my histamine in check for now, I'll see if the half tablets work and report back after I've had time to fully assess.

I don’t normally leave reviews but I feel the need to share my experience. For many years I have suffered from strange symptoms like brain fog, joint pain, low energy, and in the last 7 years, rosacea. I have had many tests run and tried everything you can imagine to try and get rid of the rosacea. Recently, I came across some information on a link between rosacea and high histamine levels/low DAO in the body. All I could think was this is me! I started researching and decided to give a DAO supplement a shot along with a low histamine diet. From the very first pill, I noticed an immediate difference after I ate. Used to, I hated eating breakfast because I always felt bad. But with the DAO my head felt clear and I did not have the normal slump period. At first I thought maybe it was a placebo effect because I desperately wanted this to be the answer for me but then my rosacea almost completely cleared up within a week of taking this supplement and I felt like I could actually think again. I highly recommend this supplement! I am going to have my DAO levels tested soon but am fairly certain what they are going to say. Hopefully, the testing will direct me to how much I need to be taking. This supplement works so good for me!! I do want to add that this pill is not a free ticket to eat whatever you want. I cannot have most chocolate (cake, candy, etc) or any type of tomato sauce/soup. I’ll still break out in a rash. That being said, my rosacea and brain fog has improved significantly with this supplement and I’m so thankful!

I've had rosacea for about six years. I've tried all kinds of creams, supplements, laser treatments, diet changes; nothing stopped the hot, painful facial flushing. After doing a ton more research and tracking my symptoms, I came to the conclusion that my rosacea is either caused or heavily influenced by a histamine intolerance or possible MCAS (which I suspect is caused by SIBO, but that's a whole nother beast). I was starting to flush after nearly every single meal, it was getting unbearable. I started experimenting, adding in several antihistamines a day along with this supplement. I slowly worked my way up to 1 entire pill since I was a bit scared of a bad reaction after reading some of the negative reviews. Luckily my body adapted fine. The first few times I took it, my chronically stuffy sinuses unclogged within literal minutes, it was weird but awesome (sadly didn't last!). More importantly, this supplement has made a HUGE decrease in my food-induced flare ups. Along with my regimen of antihistamines (h1 and h2 blockers) my after-meal flushing has become basically nonexistent, the change is almost unbelievable. Because I'm flushing less from meals, it means I'm flushing less all day long since my skin is staying calmer overall. Unfortunately it doesn't work on alcohol, I definitely still flush from that, but I had to test it lol. That leads me to the only drawback: the price. I've already gone through several boxes of these and it's only been a few months. I'm fortunate that I only need one pill for each meal and that I only eat twice a day, but man, I can't imagine if you needed several pills per meal and ate three full meals a day. And these are one of the cheapest DAO supplements on the market! Yikes. It's not sustainable, at least not for me, especially since I have a pretty large regimen of other supplements I need to pay for. I've considered 1. switching to eating one meal a day to save on costs, 2. going a strict anti-histamine diet to see if that decreases my need for the supplement, 3. growing my own pea sprouts (apparently they're high in DAO; who knew) 4. and/or cutting the pills in half to make them stretch further (you'll most likely need a pill cutter if you do this, these are HARD to cut with a knife). I even tried skipping them and just using my antihistamines only before meals to see if I could do without them but sadly, that didn't prevent a flush. As soon as I felt the flush coming on I quickly took one and my skin calmed down within minutes, so I know these are having a big impact all on their own. For now I plan to keep taking them despite my crying wallet, but I'm hoping I can get to the root cause of my histamine intolerance so that some day I no longer need them.

This product has been a game changer for someone with a mild histamine intolerance. For something I thought was IBS, NATURDAO has helped me significantly and is much more effective than other DAO products on the market. I highly suggest trying, I usually take once a day at night.

I take DAO due to a genetic mutation. I don’t produce enough DAO to breakdown histamine. So, I’ve tried a lot of DAO’s. This product did NOT work at all. Don’t waste your money.

This supplement was made a huge life saver for me. I’ve developed histamine intolerance and would get hives after eating gluten, soy or alcohol. Now take one pill before eating and the hives are mostly gone. I highly recommend.

Bought this for a family member with mast cell activation in a bad flare. This is the first DAO product we have tried. First off, I have noticed this product is 7 or 8 times the amount of DAO typically used in research and in other products. I wonder if the increased dose is why so many people claim to feel better on this product than others? Second, family member could not swallow the pills, so I ended up using a pill splitter and pill crusher to give in some applesauce. I gave only 1/4 a tablet at each meal to start. I cannot say if this has reduced the effectiveness of the product, but we are seeing slow and steady improvement without having to make drastic reductions of foods in the diet, like previously. Other supplements to reduce mast cells are also being used, but this is the only new supplement this round. I think it has made a difference in improving recovery time. I would recommend a trial of this product to anyone who thinks they may have histamine intolerance or mast cell issues. UPDATE: Like with many things mast cells, this showed improvement in the beginning and then started to go downhill. I figured out that the inactive ingredient stearate was causing the problem--in this and other supplements. I believe the DAO itself was helping but we got shot in the foot by inactive ingredients that can be problematic for people with MCAS. NOTE TO COMPANY: Please consider your inactive ingredients more carefully given the population you are marketing to.