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🦴 Keep your XL companion pest-free and unstoppable!
Bayer K9 Advantix II offers six monthly topical treatments designed for extra-large dogs over 55 lbs, delivering fast-acting, water-resistant protection that kills fleas within 12 hours and repels and kills ticks and mosquitoes. Vet-recommended and EPA-approved, it safeguards your dog against dangerous pests and tick-borne diseases for up to six months with easy application.













| ASIN | B004QRJJ0K |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | Senior |
| Allergen Information | Crab |
| Best Sellers Rank | #55,370 in Pet Supplies ( See Top 100 in Pet Supplies ) #69 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.6 out of 5 stars 16,406 Reviews |
| Global Trade Identification Number | 00724089204295 |
| Included Components | Tablets |
| Item Form | Topical |
| Item Type Name | Advantix |
| Item Weight | 0.1 Pounds |
| Item form | Topical |
| Item volume | 24 Milliliters |
| Item weight | 0.1 Pounds |
| Manufacturer | K9 Advantix |
| Manufacturer Part Number | 86315068 |
| Model Number | 81520429 |
| Scent | water |
| Scent Name | water |
| Target Species | Dog |
| UPC | 024089616501 724089204295 |
| Unit Count | 6 Count |
| Volume | 24 Milliliters |
B**N
Certainly the Best for Ticks
My dog is a Great Pyrenees at 100lbs. I use one of these per month as per the directions. Never knew if it worked until today. Found a handful of ticks I picked off in the parking lot after some grass on my dog, then one more 30 minutes later when I got home on her inner thigh that was half curled up and unresponsive. Hours later even after a thorough tick check I find what looks like dirt on her tail area, picking it up with a glove to see it was a deer tick completely dead and unresponsive. No ticks had ever bitten her at all. Fantastic product! Saves my dog, me, and anyone else in my household - they don’t just fall off they just die. Thank you!
Y**N
The safest and most effective tick protection - ticks fall off just from touching the fur
I brought my dog to West Virginia, and thank God for Advantix II — because I’ve been finding half-dead ticks every single day (no joke) in places where she sleeps or rests. At first, I was confused. I thought "repels ticks" meant it would work like bug spray does for mosquitoes, keeping them away completely. But after looking into the active ingredient, permethrin, I realized that in this case, “repel” means: once a tick touches the treated fur, it becomes so irritated or neurologically impaired that it can’t bite, can’t hang on, and eventually just falls off and dies. That’s still so much better than PetArmor, Frontline, or any of the oral preventatives (like Simparica or NexGard), which require the tick to bite the dog before it dies. No thanks. Every tick I’ve found so far had already dropped off my dog before it had a chance to bite her and feed — exactly what you want in a tick-heavy area. I’ve also tried Wondercide (cedar oil). It works okay for fleas, but it’s just not effective for ticks, especially not in the long term. Its protection wears off after 2–4 hours. I learned the hard way — my dog caught Lyme disease, developed joint pain and a limp. Thankfully, doxycycline helped and she’s okay now, but it required a full 28-day antibiotic course. I would never use oral flea/tick medications. Just ask around — you’ll hear plenty of stories about dogs having seizures after taking them. For me, that risk isn’t worth it. If you have a cat at home, unfortunately Advantix II may not be right for your household — permethrin is toxic to cats (especially when wet). But if you don’t have cats, I highly recommend this product to all dog owners. Tick-borne diseases are no joke. Fleas are annoying — I’ve had to go through the nightmare of clearing an infestation — but at least they just suck blood without causing life-threatening illness. Ticks, on the other hand, can transmit Lyme, Ehrlichia, Rocky Mountain spotted fever, and more. So if you live somewhere warm, humid, grassy, or deer-heavy — do your dog a favor and get Advantix II. It’s been a lifesaver for us.
Y**N
It works and works fantastically
I've been using K9 Advantix (I and II), and I've never had to worry about ticks, fleas or mosquitos, and I live out in the woods in a state that has these critters *everywhere*. My dogs walk all around in the fenced off area of ~4 acres, which I keep mowed to 3.5 inches and only a few trees in the main backyard but a .5 acre cedar grove in the front of the house. Cedar keeps the climbing bugs at bay well enough, but walking the fence line in the back and around the 100 yd x 50 yd pond and I have to check for ticks on me when I get in. The dogs will have a couple on them, but they never get the chance to dig in, so leaving them outside a lot of the day and night doesn't concern me. When they're inside, wherever they sit or lay, they're leaving an extremely small bit of this stuff on the material that also kills the crawling critters. The pond, naturally has mosquitos, but they don't hardly land on the dogs...unfortunately they DO land on me. As I said, I've used this stuff for decades on my dogs and because of it they're not uncomfortable from biting insects and the mosquitos pretty much leave them alone or die after lighting on them and don't infect them with heartworms. Also, this is like water, so when putting it on the dogs you need to put it in several spots on their back for it to work best. Because it's a water-type stuff, no more messy, gunky oil-based junk to get all over your hands or places they lie or collect dust/dirt/etc. Overall this can't be beat since it covers pretty much any critters that would love to make a home on your dog.
M**Y
Does the job well
Works as describes does the job well
D**H
Flea reduction right away
I've always used this and it's always worked
Trustpilot
1 month ago
1 week ago