---
product_id: 257288700
title: "Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules | Supports Methylation & Healthy Homocysteine Levels for Cardiovascular, Brain & Bone Health, Gluten, Dairy & Soy-Free"
brand: "thorne"
price: "¥20832"
currency: JPY
in_stock: true
reviews_count: 5
category: "Thorne"
url: https://www.desertcart.jp/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules
store_origin: JP
region: Japan
---

# Boosts brain & nerve function Supports healthy methylation Promotes heart & blood vessel health Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules | Supports Methylation & Healthy Homocysteine Levels for Cardiovascular, Brain & Bone Health, Gluten, Dairy & Soy-Free

**Brand:** thorne
**Price:** ¥20832
**Availability:** ✅ In Stock

## Summary

> 🛡️ Unlock your body's full potential with every capsule!

## Quick Answers

- **What is this?** Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules | Supports Methylation & Healthy Homocysteine Levels for Cardiovascular, Brain & Bone Health, Gluten, Dairy & Soy-Free by thorne
- **How much does it cost?** ¥20832 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Pure Formula:** Gluten-free, soy-free, shellfish-free capsules designed for mindful wellness.
- • **Genetic Wellness Ally:** Ideal for MTHFR genetic disorder support—stay ahead of your health game.
- • **Holistic Health Boost:** Targets heart, brain, nerve, and bone health in one powerful formula.
- • **Clinically Trusted Brand:** Chosen by 100+ pro sports teams & top healthcare practitioners in 2023.
- • **Precision Methylation Support:** Active methylated folate (5-MTHF) & B12 for superior absorption and genetic edge.

## Overview

THORNE Methyl-Guard delivers 180 capsules of active, methylated folate (5-MTHF), vitamin B6, B12 (methylcobalamin), and betaine to support healthy methylation, heart, brain, nerve, and bone health. Trusted by professional athletes and healthcare practitioners alike, this gluten-free, soy-free, and shellfish-free supplement is designed for adults seeking advanced genetic and cardiovascular wellness.

## Description

Best Sellers Visit the store Best Sellers Visit the store Sports Performance Visit the store Sports Performance Women's Health Visit the store Women's Health

Review: Excellent product for MTHFR genetic disorder - Excellent product for MTHFR genetic disorder
Review: Customer - Great product and always excellent service.

## Features

- Methylation: Support for healthy methylation
- Multiple Functions: Support for heart, blood vessel, brain, nerve, and bone health
- Homocysteine: Promotes homocysteine metabolism
- Active Bs: Contains the active, methylated forms of folate and vitamin B12 (5-MTHF and methylcobalamin)
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the 1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0012FJVA2 |
| Age Range Description | Adult |
| Allergen Information | Shellfish Free |
| Best Sellers Rank | #3,403 in Health ( See Top 100 in Health ) #240 in Multiple Vitamin-Mineral Combination Supplements |
| Brand | THORNE |
| Brand Name | THORNE |
| Color | red |
| Container Type | Bottle |
| Country of Publication | USA |
| Customer Reviews | 4.7 out of 5 stars 2,752 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Global Trade Identification Number | 00693749787037 |
| Item Dimensions | 7.3 x 7.3 x 13.3 centimeters |
| Item Form | Capsule |
| Item Weight | 180 Milligrams |
| Item form | Capsule |
| Item weight | 180 Milligrams |
| Manufacturer | Thorne Research |
| Manufacturer Part Number | SF787-R |
| Material Features | Gluten Free, Soy Free |
| Material Type Free | en_AE |
| Model Name | SF787 |
| Number of Items | 1 |
| Primary Supplement Type | Vitamin B and Folate |
| Primary supplement type | Vitamin B and Folate |
| Product Benefits | Bone & Joint Support, Brain Health Support, Heart Health Support, Nerve Support |
| Specific Uses For Product | Heart |
| UPC | 693749787037 885335121343 884733360033 885100656025 881619227596 |
| Unit Count | 180.0 Count |
| Unit count | 180.0 Count |

## Product Details

- **Age range (description):** Adult
- **Brand:** THORNE
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 7.3 x 7.3 x 13.3 centimeters
- **Item form:** Capsule
- **Item weight:** 180 Milligrams
- **Primary supplement type:** Vitamin B and Folate
- **Product benefits:** Bone Health Support
- **Unit count:** 180.0 Count

## Images

![Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules | Supports Methylation & Healthy Homocysteine Levels for Cardiovascular, Brain & Bone Health, Gluten, Dairy & Soy-Free - Image 1](https://m.media-amazon.com/images/I/61kCTgAaeVL.jpg)

## Available Options

This product comes in different **Set** options.

## Questions & Answers

**Q: What makes Thorne supplements high quality?**
A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption.

**Q: How does Thorne test its supplements for quality?**
A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we produce. 100+ Thorne employees are dedicated to ensuring quality.

**Q: Are Thorne supplements clinically Reviewed and safe?**
A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature.

**Q: Why are Thorne products more expensive than other supplements?**
A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard.

**Q: Where are Thorne supplements made and where are the ingredients sourced from?**
A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Excellent product for MTHFR genetic disorder
*by C***Y on 11 September 2025*

Excellent product for MTHFR genetic disorder

### ⭐⭐⭐⭐⭐ Customer
*by B***T on 6 August 2026*

Great product and always excellent service.

### ⭐⭐⭐⭐⭐ Thorne B Vitamins
*by M***D on 8 August 2026*

My doctor recommended this to me many years ago because I carry the MTHFR gene defect. It works great for me! Better than any other B Complex vitamin supplement I have used.

## Frequently Bought Together

- THORNE Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12-180 Capsules
- THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules
- THORNE Berberine - Dual Action Formula with Phytosome Plus Botanical Extract - Support Heart Health, Immune System, Healthy GI, Cholesterol* - Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings

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**Shop now:** [https://www.desertcart.jp/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules](https://www.desertcart.jp/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules)

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-08-16*