---
product_id: 2555579
title: "DERMA-E Anti-Wrinkle Renewal Skin Cream, 4 Oz | Lightweight facial moisturizer with retinol, panthenol & vitamin E to smooth & renew skin, helps reduce fine lines & wrinkles"
brand: "derma e"
price: "¥6718"
currency: JPY
in_stock: true
reviews_count: 13
category: "Derma E"
url: https://www.desertcart.jp/products/2555579-derma-e-anti-wrinkle-renewal-skin-cream-4-oz-lightweight
store_origin: JP
region: Japan
---

# Reduces fine lines & wrinkles 100% vegan & natural formula Deep hydration & skin renewal DERMA-E Anti-Wrinkle Renewal Skin Cream, 4 Oz | Lightweight facial moisturizer with retinol, panthenol & vitamin E to smooth & renew skin, helps reduce fine lines & wrinkles

**Brand:** derma e
**Price:** ¥6718
**Availability:** ✅ In Stock

## Summary

> ✨ Unlock timeless skin with nature’s cleanest anti-aging secret!

## Quick Answers

- **What is this?** DERMA-E Anti-Wrinkle Renewal Skin Cream, 4 Oz | Lightweight facial moisturizer with retinol, panthenol & vitamin E to smooth & renew skin, helps reduce fine lines & wrinkles by derma e
- **How much does it cost?** ¥6718 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/2555579-derma-e-anti-wrinkle-renewal-skin-cream-4-oz-lightweight)

## Best For

- derma e enthusiasts

## Why This Product

- Trusted derma e brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Age-Defying Powerhouse:** Clinically proven Vitamin A (Retinyl Palmitate) smooths and renews skin texture.
- • **Eco-Friendly Packaging:** Sustainably packaged to align with your values and elevate your skincare routine.
- • **Clean & Conscious Beauty:** 100% vegan, cruelty-free, and free from parabens, sulfates, GMOs, and harsh chemicals.
- • **Hydrate & Nourish All Day:** Rich antioxidant Vitamin E and Panthenol deliver lasting moisture without greasiness.
- • **Multi-Use Daily Essential:** Perfect for day and night use, under makeup or solo, for a fresh, youthful glow.

## Overview

DERMA-E Anti-Wrinkle Renewal Skin Cream is a 4 oz vegan, cruelty-free moisturizer formulated with Vitamin A, Vitamin E, Panthenol, and Allantoin to visibly reduce fine lines and wrinkles while deeply hydrating and renewing mature skin. Designed for daily use, it supports skin cell turnover and antioxidant protection in a lightweight, non-greasy formula housed in eco-friendly packaging.

## Description

desertcart.com: DERMA-E Anti-Wrinkle Renewal Skin Cream, 4 Oz | Lightweight facial moisturizer with retinol, panthenol & vitamin E to smooth & renew skin, helps reduce fine lines & wrinkles : Beauty & Personal Care

Review: Good job, Derma-E! - VERY happy with this line of Derma-E products (the anti-wrinkle, Vitamin A line in the new red and white containers; have not tried the others). Used the older formulation of this Derma-E cream years ago and liked a good deal. At that time, to my knowledge, Derma-E was not making much other than this cream. Stopped using the cream--why, I can't recall--and in an effort to find skin care products that were really right for my temperamental, mature, delicate redhead's skin, and to stop using make up on a daily basis, I went through an expensive but fun phase of trying some top skin care products. Tried Tata Harper (sublime and highly effective, but ridiculously priced), Dr. Hauschka (nice--still use their redness-reducing rose cream--but uneven across products, and pricey), and then settled for a while on L'Occitane's "Divine" line. But when it was time to replace my long-lasting jar of Divine creme I realized I did not want to continue to pay what it costs and that, honestly, while a nice product, it effectiveness on my skin does not justify its cost. Then saw the new lines of Derma-E, and decided to try several Anti-Wrinkle products. Am very pleased with the four products have been using for several months--this cream, the night serum, an eye cream, and an exfoliating scrub--all in this line. Each applies easily, a little goes a long way, is lightly if at all fragranced, and reasonably priced. And effective, meaning that lines, discoloration, redness, and pores are reduced, while skin appears fresher and brighter due to the gentle exfoliating effects of Vitamin A. This moisturizer, in particular, is a workhorse: very little is needed to smooth and calm my skin, and my skin looks relaxed and less lined once applied and since I've been using it. One word of warning: this is a cream of moderate richness. In humid conditions I find myself using only a very light application. Now, in colder, drier conditions, I am applying a bit more. As said, my skin is aging and not as oily as when I was younger; this cream could be on the heavy side for anyone with an oily complexion. A quick word on sorting through the maze of skin care products aimed at women. Someone I read online, a skin care expert whose name I do not recall, recommends using products that are not only free of unwanted chemicals, but that contain substances that have been shown to be effective at addressing whatever skin care issue one has. Vitamin A (retinol), she wrote, has been shown to promote skin cell turnover, or exfoliation. Vitamin C, apparently, has been shown to strengthen collagen. And Vitamin E has been shown to possess anti-oxidant properties. While it can be nice to use a product that contains exotic-sounding ingredients from plants of faraway lands, nearly none of these products have been shown to actually do what manufacturers claim they do. Nicely, Derma-E has chosen to put A, C, and E in nearly all of its products, and I think one can see the results. And not break the bank while using them!
Review: A light cream which does actually help - I discovered Derma E moisturizing renewal cream accidentally. I had received a smaple sized bottle of their salt scrub which I love, and went tookiong for more when my small jar was used up (though it did last me more than a month)! I first found it on their site, and they were sold out of the scrub. I got a few other products to try. This is my favorite of those I tried. It is a light cream but very moisturizing. After using it for about a week I have noticed a difference in the health and texture of my skin. I had been using a moisturizer (Algenist) which is 5-10 times as expensive. I love Algenist's night cream (solid serum) and will keep using that, but really like this for daytime use. As previously noted, it is a light cream which is very moisturizing. It does not have much of a scent. It is not sticky or greasy, It does not absorb (nothing does!) but sheers out well and does not leave a thick layer on your skin. It contains retinal which is one of a very few proven clinical ingredients. Many of their products use botanicals of established merit (chamomile, aloe, lavender, oat milk). I like all of the products of theirs I have tried, but this and the salt scrub are my favorites. When I discovered it was available on subscription at desertcart I added it to my order. I actually got this as part of a set, but like this better than their other "anti-aging" products. It is more pleasant to use than many others and I have seen results, which is why I subscribed before I am halfway through with my first jar.

## Features

- ANTI-AGING MOISTURIZER: This potent, age-defying moisturizer is formulated to deeply nourish aging skin. The advanced wrinkle treatment cream helps to diminish signs of aging leaving facial skin soft, smooth and supple.
- SKIN RENEWAL & REJUVENATION: This luxurious anti-wrinkle renewal cream contains Vitamin A (Retinyl Palmitate) commonly referred to as the ‘skin vitamin’ which helps to refine skin as it promotes hydration.
- ALL NATURAL FORMULA: The vegan anti aging face cream is enriched with antioxidant Vitamin E, skin-calming Allantoin and Panthenol, and nourishing oils to help improve the appearance of fine lines and wrinkles
- DAILY SKIN CARE: For best results, use twice daily as both an anti-wrinkle night cream and day cream. After cleansing, apply a rich layer of the Retinyl Palmitate cream. This wrinkle cream for women works great under makeup
- DERMA E: Clean beauty products that harness nature’s most effective ingredients. 100% vegan and cruelty-free, our eco-ethical skin care products contain no parabens, sulfates, mineral oil, petrolatum, lanolin, gluten, soy or GMOs, and are supplied in recyclable packaging.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00021KD2C |
| Active Ingredients | Vitamin E, vitamin_e |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #20,061 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #512 in Face Moisturizers |
| Brand | Derma E |
| Brand Name | Derma E |
| Container Type | Bottle |
| Country as Labeled | United States |
| Customer Reviews | 4.4 out of 5 stars 4,753 Reviews |
| Global Trade Identification Number | 00030985004809 |
| Item Dimensions | 2.8 x 2.8 x 2.8 inches |
| Item Form | Cream |
| Item Type Name | food |
| Item Volume | 118 ml |
| Item Weight | 4.6 ounces |
| Item dimensions L x W x H | 2.8 x 2.8 x 2.8 inches |
| Manufacturer | derma e |
| Manufacturer Part Number | B001ET7824 |
| Material Features | Vegan |
| Material Type Free | GMO Free |
| Model Name | Derma E Anti Cream Oz |
| Model Number | 0480 |
| Number of Items | 1 |
| Other Special Features of the Product | Not-Applicable |
| Product Benefits | Anti-Aging, Fine Line Treatment, Refining, Fights the signs of aging, The look of fine lines and wrinkles is diminished with Vitamin A, skin renewal, Renews dehydrated skin, Wrinkle Treatment |
| Recommended Uses For Product | Hydrating, Nourishing |
| Scent Name | Unscented |
| Skin Care Application Time | Anytime |
| Skin Type | Mature |
| Special Feature | Not-Applicable |
| Special Ingredients | antioxidant Vitamin E, skin-calming Allantoin and Panthenol, and nourishing oils |
| Specific Uses For Product | Aging, Fine Line, Wrinkles |
| Target Use Body Part | Face, Neck |
| UPC | 030985004809 674276066307 |
| Unit Count | 4 Ounce |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Derma E
- **Item Volume:** 118 ml
- **Item dimensions L x W x H:** 2.8 x 2.8 x 2.8 inches
- **Special Feature:** Not-Applicable

## Images

![DERMA-E Anti-Wrinkle Renewal Skin Cream, 4 Oz | Lightweight facial moisturizer with retinol, panthenol & vitamin E to smooth & renew skin, helps reduce fine lines & wrinkles - Image 1](https://m.media-amazon.com/images/I/61rmjrsIu5L.jpg)

## Questions & Answers

**Q: What is the difference in benefits between this and the vitamin C products?**
A: Although both products help to act as anti aging skincare regimens they are very different in the formulas and how they work.
Anti Wrinkle contains the skin vitamin Vitamin A to help enhance cellular renewal and diminish the appearance of fine lines and wrinkles.  
The Vitamin C platform contains Vitamin E which helps to support collagen health while also reducing the appearance of uneven skin tone, freckles, spots along with fine lines and wrinkles.

**Q: How much vitamin a iu's per say a nickel size dollop?**
A: When my skin was younger and more oily.... I would buy "Aloe Vera Fruit of the Earth "  and mix a nickle  plus and a TBS of the Aloe Vera together.   I love Aloe Vera "Fruit of the Earth"  no fragrance or color added.    You can use aloe all day long and never break out !!  And I still use it ... My skin looks like I am 40ish and I am 54 yo.   Cheers !!

**Q: is there an expiration date?**
A: Yes, although I would not recommend this product. I'm sure that they have a vitamin world near you. Their retinol cream is superior to this product.

**Q: Is the wheat germ oil overly refined so its safe for those allergic to wheat? Meaning is it gluten free?**
A: yes!The wheat germ oil is so refined that the allergens don't pass to the oil.2nd)You probably are allergic to ingest wheat derivatives and the oil contained in the cream is used to form a barrier to maintain the skin humidity. So, there is no chance you have allergy, even if you eat the cream, that is not the case.Rgds,Marfan

## Customer Reviews

### ⭐⭐⭐⭐⭐ Good job, Derma-E!
*by C***M on October 27, 2017*

VERY happy with this line of Derma-E products (the anti-wrinkle, Vitamin A line in the new red and white containers; have not tried the others). Used the older formulation of this Derma-E cream years ago and liked a good deal. At that time, to my knowledge, Derma-E was not making much other than this cream. Stopped using the cream--why, I can't recall--and in an effort to find skin care products that were really right for my temperamental, mature, delicate redhead's skin, and to stop using make up on a daily basis, I went through an expensive but fun phase of trying some top skin care products. Tried Tata Harper (sublime and highly effective, but ridiculously priced), Dr. Hauschka (nice--still use their redness-reducing rose cream--but uneven across products, and pricey), and then settled for a while on L'Occitane's "Divine" line. But when it was time to replace my long-lasting jar of Divine creme I realized I did not want to continue to pay what it costs and that, honestly, while a nice product, it effectiveness on my skin does not justify its cost. Then saw the new lines of Derma-E, and decided to try several Anti-Wrinkle products. Am very pleased with the four products have been using for several months--this cream, the night serum, an eye cream, and an exfoliating scrub--all in this line. Each applies easily, a little goes a long way, is lightly if at all fragranced, and reasonably priced. And effective, meaning that lines, discoloration, redness, and pores are reduced, while skin appears fresher and brighter due to the gentle exfoliating effects of Vitamin A. This moisturizer, in particular, is a workhorse: very little is needed to smooth and calm my skin, and my skin looks relaxed and less lined once applied and since I've been using it. One word of warning: this is a cream of moderate richness. In humid conditions I find myself using only a very light application. Now, in colder, drier conditions, I am applying a bit more. As said, my skin is aging and not as oily as when I was younger; this cream could be on the heavy side for anyone with an oily complexion. A quick word on sorting through the maze of skin care products aimed at women. Someone I read online, a skin care expert whose name I do not recall, recommends using products that are not only free of unwanted chemicals, but that contain substances that have been shown to be effective at addressing whatever skin care issue one has. Vitamin A (retinol), she wrote, has been shown to promote skin cell turnover, or exfoliation. Vitamin C, apparently, has been shown to strengthen collagen. And Vitamin E has been shown to possess anti-oxidant properties. While it can be nice to use a product that contains exotic-sounding ingredients from plants of faraway lands, nearly none of these products have been shown to actually do what manufacturers claim they do. Nicely, Derma-E has chosen to put A, C, and E in nearly all of its products, and I think one can see the results. And not break the bank while using them!

### ⭐⭐⭐⭐⭐ A light cream which does actually help
*by E***E on July 10, 2020*

I discovered Derma E moisturizing renewal cream accidentally. I had received a smaple sized bottle of their salt scrub which I love, and went tookiong for more when my small jar was used up (though it did last me more than a month)! I first found it on their site, and they were sold out of the scrub. I got a few other products to try. This is my favorite of those I tried. It is a light cream but very moisturizing. After using it for about a week I have noticed a difference in the health and texture of my skin. I had been using a moisturizer (Algenist) which is 5-10 times as expensive. I love Algenist's night cream (solid serum) and will keep using that, but really like this for daytime use. As previously noted, it is a light cream which is very moisturizing. It does not have much of a scent. It is not sticky or greasy, It does not absorb (nothing does!) but sheers out well and does not leave a thick layer on your skin. It contains retinal which is one of a very few proven clinical ingredients. Many of their products use botanicals of established merit (chamomile, aloe, lavender, oat milk). I like all of the products of theirs I have tried, but this and the salt scrub are my favorites. When I discovered it was available on subscription at Amazon I added it to my order. I actually got this as part of a set, but like this better than their other "anti-aging" products. It is more pleasant to use than many others and I have seen results, which is why I subscribed before I am halfway through with my first jar.

### ⭐⭐⭐⭐⭐ Excellent moisture
*by A***. on March 19, 2025*

The day I received it, I used it at night. I applied the cream all over my face, around my eyes, and neck. I'm 49, have fair, sensitive, dry skin. I was looking for a good moisturizing anti-wrinkle cream without feeling greasy and without a heavy odor. More importantly, I was looking for a cream that the moisture lasts till morning. Because most of the creams moisture doesn't last when you wake up. This product exceeded my expectations, it doesn't feel greasy, almost no odor, smells very clean, very very light smell, I don't know smell may be due to glycerin and you feel the velvety soft light glycerin moist without feeling uncomfortable like how a very hot summer humid day can be uncomfortable on skin. Very well balanced of glycerin, safflower oil along with other oils which could end heavy cream, but not. This cream for sure can be my day and night cream, under make-up kind of primer/moisturizer cream too. Summer-winter cream. I am very glad I run into this cream. Please keep up the good work and good price. Thanks. My opinion every type of skin can use this cream.

## Frequently Bought Together

- Derma E Anti-Wrinkle Renewal Skin Cream – Vitamin A Wrinkle Treatment Cream – Vegan Anti-Aging Moisturizer to Smooth & Renew Aging Skin, 4 oz
- Derma E Anti-Wrinkle Cleanser – Anti-Aging Face Wash with Glycolic Acid and Vitamin A – Gentle Cleansing and Exfoliating Facial Wash Removes Makeup, Oil and Impurities, 6 oz
- Derma E Vitamin E 12,000 IU Cream – Moisturizer for Face and Body – Multi-purpose Face Cream, Hand Cream and Body Lotion Soothes and Protects, 4 oz

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-08-28*