Life Extension Optimized Folate L-Methylfola 1000 Mcg Vegetarian Tablets, 100 Count

FABULOUS!! Life changing for a member of my family. AND, this worked better than the prescription methylfolate. The LE is bound to a glucosamine while the Rx is bound to calcium. I do not understand why this works better than the Rx but perhaps the calcium vs. glucosamine is the reason. If you have the genetic inability to absorb folic acid this is THE answer. I am shocked at how quickly my family members life changed as a result of this supplement. She started by taking 15 a day (to make it equivalent to the Rx) and within a day or two I couldn't believe the difference. Within a week she was a new person! It was unbelievable!! Then she ran out of the supplement....day one she could not walk easily, day two she could not speak properly or understand those around her, day 3 she could hardly move. She ran out and filled the Rx as she could not find this product in her small town. She anxiously took the Rx waiting for the same miracle to occur. Day 1, not much improved, day 2 - minor improvements, day 3 - daunting realization that the LE product is better than the Rx, day 4 - overnighted the LE product to her home, day 5 - took both the supplement and Rx. She began a downward spiral. CONCLUSION: the LE supplement is BETTER than the Rx for her and the Rx interferes with absorption of the supplement. This is just her experience and everyone is different but I wanted to share this story as the pharmacists were all telling her the Rx was better and all the supplements were the same. She has since tried other supplements and they are not as effective. If you think you have the genetic inability to metabolize folic acid try this. As a result of her dramatic turn around her doctor is now aggressively appealing the rejection she received from her insurance company for the genetic test. Do not wait for doctors and insurance companies to make/break your life! Her symptoms (which are now gone) included: non-existent short term memory, ADD, anxiety, extreme fatigue, muscle weakness, falling, impulsiveness, inability to follow through on anything, and much more. She had been diagnosed with EVERYTHING except the actual disease. Yea, Life Extension. We love you!!

Not to exaggerate, but this supplement is pretty life-changing. Improved my mood and energy immensely within a couple of hours. Expensive but definitely worth it.

I have been suffering from depression for a long time. I feel a little better now. Doing exercises. I can not tell if this medication helped. But surely I did not feel any side effects. As a precusor of hormones linked to depression, I guess there is no harm using them. I will keep using. I think it could have improved a little.

It is 2021 and global warming is upon up, and landfills are filling up with plastic that is not recycled. I purchased 3 bottles of this product. Each bottle contains 100 tablets. I was able to combine all three bottles into one and there was STILL a lot of space left at the top of the bottle. This is wasteful, and adds to the pollution stream. I don't care how good the actual tablets are, I won't be purchasing again unless the company addresses this issue.

Much more effective in addressing MTHFR symptoms than any other form of folate I've tried. I believe I've trialed each of the forms currently available in the US and effects ranged from no change to making me sicker than before. The only prescription form of folate currently available, Deplin, resulted in the worst increase in symptoms. There are multiple forms of folate. Yet as it stands now, single large pharmaceutical company holding the monopoly on "prescription folate" [essentially a naturally occurring substance, which to the best of my understanding they have notcontributed to the development of in the slightest] is opting to produce one form only, using cheaper ingredients than most of the the nonprescription forms. So I guess let's hope fellow MTHFRs, that they don't go after life extensions right to make this form. Good luck on your quest for better health.