N1O1 Nitric Oxide Activating Anti-Aging Face Serum, 20% Vitamin C, 1 Fl Oz | Developed by Dr. Nathan S Bryan, Hydrating Serum, Minimizes Dark Spots, Promotes Smoother-Looking Skin, Reduces Fine Lines

Three years ago, I cut my face right in between my eyebrows. I got left with a 1/4” scar that ran deep, extended my wrinkle and gave me a permanently worried look. It got worse over time. My trusty moisturizer helped everywhere, except for the scar. The need to do something overcame my skepticism about nitric oxide, so I decided to give it a chance. I had no expectations. The instructions recommend daily application. I applied about twice a week. For a couple weeks, there was no change. Maybe a month later I noticed the scar is no longer joined to my eyebrow wrinkle, reducing my angry, worried look. I began applying every other day and after a few more weeks, the scar is now flat and only visible within a few feet distance. By flat I mean no longer deep, almost completely flush with the skin, with a very slightly discolored center. The scar basically shrank in size and almost disappeared optically. My wrinkles also improved substantially. I now believe that the scar will disappear completely with another few weeks of frequent use. I started to apply all over my face and neck, since the minimum dose is large enough. I’m now administering to whoever asks: seniors, youth, children, … whoever has skin damage. The cream itself clogs pores a little so I shower it off at the end of the day. It’s not suitable for wearing light colors as it can stain them yellow. I wish it came in glass instead of plastic. I thought I’d keep my scar for the rest of my life, looking progressively angrier as I age. And yet, here we are - I’ve reversed three years of skin damage. Thank you Dr. Nathan Bryer!

This is my no. 1 go-to serum. I have been using it since 2021 and have seen a great improvement in the smoothness of my skin, particularly around my eyes. One morning in 2021, I looked in the mirror and it was like somebody pulled a switch. The delicate skin around the eyes, that had been fairly smooth, suddenly sagged and looked baggy. None of my existing products did anything. Fortunately, I saw a TV commercial for the N1O1 serum and decided to give it a try. Since I am a woman of a certain age, I followed the instructions and began using it twice a day, with emphasis on the eye area. I have sensitive skin around the eyes and on the cheeks. There was, and still is, no irritation. Within about 3 days, there was improvement. The skin looked much more lifted. The whole eye area began to smooth out. In fact, since I was applying the serum over my whole face, my facial skin began to look smoother. Pores looked smaller, and the skin tone was more even. The effect of the serum seems to build over time. I continue to use the serum every day and am very pleased with the results.

Excellent product, very easy to use.

It doesn’t, last long enough to give a good review.

Been using NO serum for years! Truly unique product/foundation to build ur layered skin care routine upon. Gives the skin a glow and I feel my mature skin needs it. 4 stars because of the uneven dosage. Runs out of the clear liquid before the Vit C pumps. This is an ongoing design problem and the company is aware of it which is why Dr. Bryant's site no longer sells it. Resulting is less dosages than than claimed. That said, I'm willing to accept this flaw and continue the pneuma glow.

I was having horrible skin months, maybe years, red blotchy broken out, dry patches I kept digging at it and it refused to heal or retain moisture. My 30’s were mixed skin but my 40’s were just bad, bag on head horrendous. I bought it on a Sat same day delivery. I’m shocked, near 6 days later I’m writing a review. The dry patches are gone. The breakouts gone. The redness and scars are slower to respond but, I think eventually that will fade as well. If I can ditch makeup I’d call this a complete game changer. My skin did lightly flush initially but it goes away quickly for me. I’m excited to see what a month out looks like. These pictures are a 7 days using the serum post wash twice a day followed by my normal moisturizer. Maintaining my makeup routine. This comes highly recommended by me!

Classic vitamin C scent (not like oranges, but vitamin C serums its how I knew this had real Vitamin C in it. Its a very distinct smell. My skin wasn't too keen on this serum however. I had high hopes; maybe too high really. It eventually started leaving my skin with a slight orange tint. At the time I was using this and just a nightly moisturizer. It was this product that did it. I always test out products in as singualr a way as possible so i can determine how it works on me. This missed all the marks. It did leave my skin soft and smooth. But no other noticable benefits (no smoother skin texture, no decrease in wrinkles or fine lines) This is just an overglorified vitamin C serum, nothing more. Its wasn't even that effective as a vitamin C serum. The only thing it did do was turn my skin slightly orange so I looked like I had a bad fake tab :/ Disappointed over this product. But I tried it and now never have to wonder again. Its not for me. For reference - im a light skin tone (fair/light) I easily (and only) burn in the sun. I cannot tan at all (literally never have tanned its impossible for me) I have normal skin that isn't sensitive to products, no acne (a pimple here and there sometimes) and neither dry or oily skin, its relatively helathy overall. Reddish tone overall (mainly cause blood flow is super noticeable think in terms of full face flushing almost all tue time)

I have listened to scores of videos about the science behind these products. But I am not one to spend this kind of money on skincare. However, my husband has been having problems with itchy skin on his back for well over a year now. This has not been mild, but severe— bad enough that he has been to a dermatologist several times to try to find a fix. Bad enough that he has had to get up and leave meetings, and it often wakes him up at night. It has been making him truly miserable. Nothing has helped. It isn’t cheap to go to the doctor, so I spent the $120 to give this a try. The itching on his back went away within seconds of applying this serum. Wow!! It seems to stop the itching for several days. We are still working on how often it needs to be applied, but we are stunned that this has been magic! I am in my 60s, and of course have begun using it on my own skin as well! :) I may write a separate review about that later, but there are already many wonderful testimonials here in the comments. If you have strange skin problems, I think this product is worth a try. Update: My daughter has fought mild acne all her life; in her 30s now. This is the first product to fix it. Her too-pale skin with a roughish texture is smooth with good, pink color. As others have said, she seems to need it daily to maintain results. But—she bought 3 bottles when the came up on sale so she doesn’t run out! The tingling and slight flushing the serum caused initially stopped after a few weeks of use. Good stuff!