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✨ Unlock your skin’s youthful glow with Nobel-winning science! ✨
N1O1 Nitric Oxide Activating Anti-Aging Face Serum combines a breakthrough nitric oxide delivery system with 20% stable Vitamin C to combat signs of aging at their source. Clinically backed and suitable for all skin types, this serum boosts collagen, evens skin tone, and hydrates deeply without harsh additives. Experience visible reduction in wrinkles, dark spots, and fine lines with a fast-absorbing formula designed for daily use.


















| ASIN | B08LNTJZST |
| Active Ingredients | vitamin_c |
| Best Sellers Rank | #42,727 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #867 in Facial Serums |
| Brand | N1O1 |
| Brand Name | N1O1 |
| Customer Reviews | 4.2 out of 5 stars 331 Reviews |
| Item Form | Serum |
| Item Volume | 1 fluid ounces |
| Manufacturer | Pneuma Nitric Oxide |
| Manufacturer Part Number | n1o1 |
| Material Features | Cruelty Free, Fragrance Free, GMO Free, Gluten Free, Vegan |
| Material Type Free | Paraben Free, Phthalate Free |
| Model Number | n1o1 |
| Number of Items | 1 |
| Product Benefits | Anti-Aging |
| Recommended Uses For Product | Before Cream |
| Scent | Fragrance Free |
| Scent Name | Fragrance Free |
| Skin Type | All |
| Special Ingredients | Antioxidants, Vitamin C, Vitamin E |
| Target Use Body Part | Face |
| UPC | 608597658903 |
| Unit Count | 1 Fluid Ounces |
| Use for | Face |
C**I
This is the one to buy!! I've tested many expensive ones!!
As I started seeing changes in my skin, I searched for solutions and was influenced into buying multiple products that had no ROI, I don't expect results over night, in fact I believe if you're using a topical, it might take months and multiple bottles to start seeing changes. That said, I still get a feel for a product earlier on. I bought this after I watched a podcast with the doctor who invented it and felt he was sincere and skilled (knowing the science is a far cry from product development) I had been frustrated with a different product (more expensive with terrible packaging) I bought this and on the first application I felt it was "real", by the first week I can see better skin emerging, I'm still mid first bottle, and now want to order more products from them. Some days I see results more than others, but I know without a doubt this works!! I'm excited to see the changes over time. The one feedback I would give the brand is on packaging, the vitamin C side sort of sprays out at times, not that it wastes product but feels like I get less than the other side. so be mindful of that when you use it. **bottom line: This is effective, absorbs right away, I barely wait to moisturize after, and I think you get a good amount for the money. -Cons: Not a true con but packaging could be better but I understand they want to control dosing, I just feel viscosity is different on both sides therefore it should be a different dispenser. This will not stop me from buying again and I HIGHLY RECOMMEND THIS!! Buy this so you start seeing results, it's refreshing
C**G
It’s worth the $100
I was having horrible skin months, maybe years, red blotchy broken out, dry patches I kept digging at it and it refused to heal or retain moisture. My 30’s were mixed skin but my 40’s were just bad, bag on head horrendous. I bought it on a Sat same day delivery. I’m shocked, near 6 days later I’m writing a review. The dry patches are gone. The breakouts gone. The redness and scars are slower to respond but, I think eventually that will fade as well. If I can ditch makeup I’d call this a complete game changer. My skin did lightly flush initially but it goes away quickly for me. I’m excited to see what a month out looks like. These pictures are a 7 days using the serum post wash twice a day followed by my normal moisturizer. Maintaining my makeup routine. This comes highly recommended by me!
F**R
Removed my scar, despite infrequent use
Three years ago, I cut my face right in between my eyebrows. I got left with a 1/4” scar that ran deep, extended my wrinkle and gave me a permanently worried look. It got worse over time. My trusty moisturizer helped everywhere, except for the scar. The need to do something overcame my skepticism about nitric oxide, so I decided to give it a chance. I had no expectations. The instructions recommend daily application. I applied about twice a week. For a couple weeks, there was no change. Maybe a month later I noticed the scar is no longer joined to my eyebrow wrinkle, reducing my angry, worried look. I began applying every other day and after a few more weeks, the scar is now flat and only visible within a few feet distance. By flat I mean no longer deep, almost completely flush with the skin, with a very slightly discolored center. The scar basically shrank in size and almost disappeared optically. My wrinkles also improved substantially. I now believe that the scar will disappear completely with another few weeks of frequent use. I started to apply all over my face and neck, since the minimum dose is large enough. I’m now administering to whoever asks: seniors, youth, children, … whoever has skin damage. The cream itself clogs pores a little so I shower it off at the end of the day. It’s not suitable for wearing light colors as it can stain them yellow. I wish it came in glass instead of plastic. I thought I’d keep my scar for the rest of my life, looking progressively angrier as I age. And yet, here we are - I’ve reversed three years of skin damage. Thank you Dr. Nathan Bryer!
K**N
Allergic Reaction - No Go
This serum broke my face and neck out with red bumps and itchy skin. I wasn't sure if it was the product so I stayed off of it for a week and then used it one more time. Huge allergic reaction and has caused me to have itchy skin and irritated skin. I do not like this product for me. I ordered it based on a segment shown on DayStar TV. Apparently Joni uses it but I can not tolerate the product.
M**H
Anti-aging secret weapon
Been using NO serum for years! Truly unique product/foundation to build ur layered skin care routine upon. Gives the skin a glow and I feel my mature skin needs it. 4 stars because of the uneven dosage. Runs out of the clear liquid before the Vit C pumps. This is an ongoing design problem and the company is aware of it which is why Dr. Bryant's site no longer sells it. Resulting is less dosages than than claimed. That said, I'm willing to accept this flaw and continue the pneuma glow.
A**D
A dual-chamber powerhouse!
Sure, the N1O1 serum is pricey--among the most expensive facial care products I have used. That said, there is one important difference compared to other products in this price range: it actually works! I am not a morning person and it shows in my face. When I wake up, my eyes are puffy, and my skin is often lackluster. At 41, I also have crow's feet and frown lines. Since I've added the serum to my post-shower morning routine (almost done with my first bottle; already have a second one to make sure I don't run out!), by the time I get to work, it's as if a mini lifting has energized my entire face. My wrinkles and frown lines are less apparent, and my complexion is brighter. I'm a college teacher and I've even had compliments from students (and they are a hard-to-impress crowd!) The biggest impacts seem temporary--if I skip a day, I definitely notice a difference--but there do seem to be some long term improvements that I notice when comparing photos. I'm very pleased this product is not scented; it also caused zero irritation, even though I apply it under my eyes. With other potent products that include vitamin C, retinol, etc., my eyes usually end up stinging after a while. Not so with N1O1. Overall, I'm extremely happy with the product and results, and I'll keep purchasing as long as my budget allows.
C**S
Bought to fix itchy skin…plus update
I have listened to scores of videos about the science behind these products. But I am not one to spend this kind of money on skincare. However, my husband has been having problems with itchy skin on his back for well over a year now. This has not been mild, but severe— bad enough that he has been to a dermatologist several times to try to find a fix. Bad enough that he has had to get up and leave meetings, and it often wakes him up at night. It has been making him truly miserable. Nothing has helped. It isn’t cheap to go to the doctor, so I spent the $120 to give this a try. The itching on his back went away within seconds of applying this serum. Wow!! It seems to stop the itching for several days. We are still working on how often it needs to be applied, but we are stunned that this has been magic! I am in my 60s, and of course have begun using it on my own skin as well! :) I may write a separate review about that later, but there are already many wonderful testimonials here in the comments. If you have strange skin problems, I think this product is worth a try. Update: My daughter has fought mild acne all her life; in her 30s now. This is the first product to fix it. Her too-pale skin with a roughish texture is smooth with good, pink color. As others have said, she seems to need it daily to maintain results. But—she bought 3 bottles when the came up on sale so she doesn’t run out! The tingling and slight flushing the serum caused initially stopped after a few weeks of use. Good stuff!
M**A
Not for me. Left an orange tint to my skin.
Classic vitamin C scent (not like oranges, but vitamin C serums its how I knew this had real Vitamin C in it. Its a very distinct smell. My skin wasn't too keen on this serum however. I had high hopes; maybe too high really. It eventually started leaving my skin with a slight orange tint. At the time I was using this and just a nightly moisturizer. It was this product that did it. I always test out products in as singualr a way as possible so i can determine how it works on me. This missed all the marks. It did leave my skin soft and smooth. But no other noticable benefits (no smoother skin texture, no decrease in wrinkles or fine lines) This is just an overglorified vitamin C serum, nothing more. Its wasn't even that effective as a vitamin C serum. The only thing it did do was turn my skin slightly orange so I looked like I had a bad fake tab :/ Disappointed over this product. But I tried it and now never have to wonder again. Its not for me. For reference - im a light skin tone (fair/light) I easily (and only) burn in the sun. I cannot tan at all (literally never have tanned its impossible for me) I have normal skin that isn't sensitive to products, no acne (a pimple here and there sometimes) and neither dry or oily skin, its relatively helathy overall. Reddish tone overall (mainly cause blood flow is super noticeable think in terms of full face flushing almost all tue time)
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