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Description

  • GeneName: AVPR2; DI1; DIR; NDI; V2R; ADHR; DIR3.
  • SynName: Anti-AVPR2 / V2R Antibody (Cytoplasmic Domain) IHC-plus; AVPR2; ADHR; AVPR V2; Avp2r.
  • Antidiuretic hormone receptor; DI1; DIR3; NDI; Vasopressin type 2 receptor.
  • Vasopressin type II receptor; Vasopressin V2 receptor; V2 vasopressin receptor.
  • Clonality: Polyclonal; *Source: Rabbit.
  • Tested: Immunohistochemistry (IHC - Paraffin); *AppNotes: IHC-P (26 ug/ml).
  • Form: PBS, 0.1% sodium azide.; *Purity: Immunoaffinity Purified; *Conc: 1 mg/ml.
  • Immunogen Type: Synthetic peptide.
  • Antigen Modification: Cytoplasmic DomainStorage: Long term: -70 degree C; Short term: +4 degree C.
  • FREE-8GB-USBDrive for this item. Item is for research use. NOT for diagnostic/therapeutic procedure..
  • Imported from USA.
*Reactivity: Gibbon, Chimpanzee, Gorilla, Hamster, Human, Monkey, Mouse, Orangutan, Rabbit, Rat Predicted Reactivity: Bat, Dog, Horse, Pig (at least 90% immunogen sequence identity); *Specificity: Human AVPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.Target Species: Human; *Immunogen Description: Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human AVPR2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit (100%).; *Immunogen: AVPR2 / V2R antibody was raised against synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human AVPR2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit (100%); Baboon, Bat, Horse (95%); Dog, Pig (90%); Armadillo (85%); Shrew, Panda, Bovine (80%).; *Accession#: NP_000045.1; NM_000054.4; P30518; *Description: The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI).; *NCBI Summary: This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule ...
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Rabbit Polyclonal to Human AVPR2 / V2R (Antibody)

Quantity
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