---
product_id: 129475025
title: "Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments"
brand: "frontline"
price: "¥20543"
currency: JPY
in_stock: true
reviews_count: 9
category: "Frontline"
url: https://www.desertcart.jp/products/129475025-plus-flea-and-tick-treatment-for-x-large-dogs-up
store_origin: JP
region: Japan
---

# 30-day continuous protection waterproof formula kills fleas, eggs, larvae & ticks Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments

**Brand:** frontline
**Price:** ¥20543
**Availability:** ✅ In Stock

## Summary

> 🛡️ Stay ahead of pests, keep your best friend itch-free and unstoppable!

## Quick Answers

- **What is this?** Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments by frontline
- **How much does it cost?** ¥20543 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.jp](https://www.desertcart.jp/products/129475025-plus-flea-and-tick-treatment-for-x-large-dogs-up)

## Best For

- frontline enthusiasts

## Why This Product

- Trusted frontline brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Defense:** One monthly dose shields your dog for a full 30 days—never miss a beat in flea & tick protection.
- • **Waterproof & Resilient:** Active ingredients deposit in skin glands, keeping your dog protected even after baths or swims.
- • **Complete Life Cycle Kill:** Targets adult fleas, eggs, larvae, and ticks to break the infestation cycle before it starts.
- • **Trusted for Over 20 Years:** Backed by decades of proven effectiveness and pet owner loyalty—join millions who rely on Frontline.
- • **Easy, Stress-Free Application:** Single spot application between shoulder blades—no mess, no fuss, just fast-acting protection.

## Overview

FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs offers a fast-acting, waterproof topical solution that kills fleas, flea eggs, larvae, chewing lice, and ticks—including those that transmit Lyme disease. Designed for dogs weighing 89 to 132 lbs, it provides continuous protection for 30 days with a single monthly application. Trusted by pet owners for over 20 years, this treatment breaks the flea life cycle and remains effective even after water exposure, ensuring your dog stays protected year-round.

## Description

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.

Review: This stuff still works great - I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on desertcart! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!
Review: Still works in my part of the state - Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...

## Features

- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07NGXYVZZ |
| ASIN  | B07NGXYVZZ |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #2,780 in Pet Supplies ( See Top 100 in Pet Supplies ) #12 in Dog Flea Drops |
| Brand Name | Frontline |
| Breed Recommendation | Large |
| Color | Red Box |
| Country of Origin | France |
| Customer Reviews | 4.4 4.4 out of 5 stars (15,105) |
| Date First Available | February 7, 2019 |
| Date First Available  | February 7, 2019 |
| Directions | 1. Part your dog's hair at the shoulder blades. 2. Apply content of applicator to the skin. 3. Repeat every 30 days for continuous protection. |
| Included Components | Applicator |
| Item Dimensions LxWxH | 1 x 5.75 x 4.5 inches |
| Item Package Dimensions L x W x H | 5.83 x 4.41 x 1.1 inches |
| Item Weight | 2.24 ounces |
| Item model number | 72220 |
| Item model number  | 72220 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer  | Boehringer Ingelheim Animal Health |
| Manufacturer recommended age  | 1 month and up |
| Model Name | Frontline Plus |
| Number of Items | 8 |
| Product Dimensions  | 1 x 5.75 x 4.5 inches; 2.24 ounces |
| Size | 8 Count |
| Specific Uses for Product | Active, Indoor, Outdoor, Parasites |
| Style | 8 Count |
| Target Audience Keyword | dogs, house-cats |
| Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. |

## Product Details

- **Active Ingredients:** fipronil and (S)-methoprene
- **Age Range (Description):** All Life Stages
- **Allergen Information:** Gluten Free
- **Brand:** Frontline
- **Dog Breed Size:** Giant
- **Item Form:** Liquid
- **Item Volume:** 32 Milliliters
- **Item Weight:** 2.24 ounces
- **Scent:** Unscented
- **UPC:** 611030624793 350604062479

## Images

![Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments - Image 1](https://m.media-amazon.com/images/I/71MDwv+VnSL.jpg)

## Questions & Answers

**Q: Besides fleas and ticks does frontline plus kill ear mites ?**
A: no

**Q: The product ad says dogs 89 to 132lbs, but the description says 45-88lbs.  My dogs are over 100lbs.  Is this the correct product?**
A: Where does it say it if for 45-88lbs? This items 'style' is 89-132lbs. This is what I get for my 3 dogs. One is 110lbs but the other two are 80lbs and 15lbs. I use a full dose for the large dog and split one for the other two. There are markings on the applicator to let you know how much you ha e used. The 15lb dog gets 1/4 dose and the 80lb dog get the remainder. It is much cheaper to buy the larger dosage and just distribute accordingly.

**Q: How do you know the expiration date of this product?**
A: FRONTLINE® Plus does not have an expiration date.

**Q: Does Frontline have a strong odor when applied?**
A: No. I never noticed an odor.

## Customer Reviews

### ⭐⭐⭐⭐⭐ This stuff still works great
*by T***E on December 29, 2025*

I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on Amazon! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!

### ⭐⭐⭐⭐⭐ Still works in my part of the state
*by S***H on September 23, 2024*

Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...

### ⭐⭐⭐⭐⭐ There ain't no bugs on Skip or Rayne!
*by R***S on November 28, 2025*

Works as it should! No fleas and no ticks! Easy to apply and lasts 90days with no weird smell.

## Frequently Bought Together

- Frontline Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 8 Treatments
- Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
- Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses

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*Product available on Desertcart Japan*
*Store origin: JP*
*Last updated: 2026-03-19*