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🐾 Protect your big pup like a pro — no pests, no worries!
K9 Advantix II XL is a vet-recommended, fragrance-free topical treatment designed for dogs over 55 lbs. It kills and repels fleas, ticks, mosquitoes, biting flies, and lice on contact—without requiring pests to bite first. Waterproof after 24 hours and effective for 30 days, it offers fast-acting, comprehensive protection with easy monthly application and no prescription needed.














| ASIN | B07NX2VWYC |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #269 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.5 out of 5 stars 49,426 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089114945 |
| Item Form | Drops |
| Item Type Name | Topical |
| Item Volume | 4 ml |
| Item Weight | 22.68 g |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 90204386 |
| Model Number | 90204386 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089114945 |
| Unit Count | 1 Count |
| Volume | 4 ml |
T**A
K9 Advantix II repels & kills through contact no biting needed
I have been using this product for over 16 years and I'm a dog trainer who has upwards of 23 dogs at a time in my home and I've never had a tick or a flea. The difference between K9 Advantix II is a fragrance free monthly topical that kills, repels fleas, ticks, flea larvae and eggs whích breaks the cycle, mosquitoes for up to 4 weeks that may transmit heartworms, kills lice, it's waterproof after 24hrs and also repels biting flies which all keeps your fur baby comfortable. In comparison, to just the K9 Advantix which only treats for fleas, mosquitoes, biting flies & lice. While other products like Frontline kills but does not repel ticks or fleas it requires them to bite your pet first and has no effect on mosquitoes or biting flies. Plus it's the only flea medication on the market that you can start during any of the four flea cycles which will stop them in their tracks all they have to do is simply touch your pet even during an infestation you will see it start taking effect within 12 hours, which you may need to apply a second dose that is perfectly safe to do so but not more. For your convenience it comes in several different sizes that apply to your pets weight from super small to extra extra large. While it provides the best protection on the market without a prescription needed it's not the cheapest product either but it's not the most expensive, it has a very average cost that ranges with the size of your pet to the multiple size pack you purchase from 1 to 6 tubes. It's also available for cats in addition to not having nasty side effects like other flea medications do. Inside the box there's even stickers which you can place on a calendar so you don't forget to apply the next dose the same day of the following month. I wouldn't choose another product that I would recommend this to anyone if you want peace of mind from something so easy to use,
T**J
Reliable product - highly recommend - works !!!
Always use this brand flea preventative . It kills many critters trying to annoy and hurt my pups . I want my fur covers kids just as safe as my flesh covered kids ;) The product is the best for fleas ticks and mosquitos . And in this heat and lack of freezing temps , ticks and rad and skeeters are running ramped out there . The size depends on your dog’s weight please read their chart within the ad . Then there are single dose , 2 pack, 3 pack and 6 packs available . It is to be used once a month . Imagine this .. the liquid seeps into your pets skin and spreads around via the oil in the skin . It gives them complete protection as far as coverage . There is not a spot a flea can bite them and survive . Most fleas and ticks will be repelled by the scent that we cannot smell once it is “ in/ on “ them . It uses your pets natural body chemistry to help it work better . You should wait at least 2 days after giving a bath to use flea protection like this . The pet needs to replenish the oils that a bath(shampoos) dries out . Then it will work better . Do not use on wet skin either . It is best to separate the hairs on your let until you see skin ( best spot usually base of back of neck where they cannot reach or lick it ) Then place the vial to the skin and squeeze gently . Be aware of your eyes !! If you have larger dogs there is more in the vial so I will do one spot then spread hairs next to that spot and apply rest in same area but different spot This way it all sinks in and it won’t run onto the hair and clump up . If it does leave it for now let it all dry after a day just brush the spot to eliminate a tangle . I have been using this product for as long as I can remember and the animal hospital I worked at recommend this product as well . It will treat more than frontline plus will . I feel better also. My dogs don’t itch all the time . There have been no reactions or issues from this product on their skin . IF ingested by pet they need to be taken to ER right away . And if ingested by humans as well-ER move it move it move it !!! Poisonous if ingested or gets into eyes of you or pet. I like the snap open vial better than the get scissors and cut open vial Doing that can cause a squirt . I always look other way when opening these and never near pets face . Always wash hands with damp after applying to pet asap. A very durable reliable product for your and your babies . A size for every pet and peace of mind for every owner / parent
A**E
Works great awesome I definitely suggested
UPDATE I don’t know what y’all all your people take your dogs to the vets instead of showing them online here that they can’t walk. The fur is falling out of the bleeding. That’s ridiculous. Take your dog to the friggin neck. Let the vet determine the cause exactly and then if it’s in clause because of this then Put a negative and state the fact that you took him to a vet and the vet did test and it was the closet because I’ve been using this product for 25 years on my dogs back then and my new dogs now my dogs I had 16 years ago dogs I had 10 years ago dogs I had 13 years ago my 16 1/2 year old cocker spaniel has had this from the day he could actually have this And I have never had a problem with that on any of my dogs especially him you know it got rid of the fleas and I noticed a few texts very easy to get off compared when I didn’t use it like if I skipped a couple of months and they had a dick and I was like oh my God and then I would try to get it off and it was a hassle. I mean, it did not pull up. Come out whatever And so I put them back on this every month originally and if they get a tick and I see it. I just need tweezers and it just pops right off no eggs inside nothing no problem with the weather did not cause any of my dogs ever itch or lose hair so I think you people have an undergoing problem with your dog that you did not address Prior to use this. Yes, I’m gonna blame you. Yes I’m blaming all you that people that has undermining problems with their dog and you don’t take them to the vet and you add this product on top of them. Yes, it probably will do something like that. SO I REPEAT, TAKE YOUR DOG TO THE GD VETERINARIAN PROFESSIONAL LET THE PROFESSIONAL DO THEIR WORK !!!! Oh, I also have one dog right now. I have three of them English mastiff and I have one of them that sits at my back gate in the dirt never has fleas never has sticks never has any. He lays in the dirt 185 pound and his head I can look it out right now his head is in it. His whole body lengthwise is in it and I swear he digs holes just you know it makes it cool.. and there’s a picture of him laying at the fence in the dirt. He loves it. I check them every day. Nobody has fleas. Nobody has anything so you people are doing something wrong. I’m gonna blame all of you. They have a problem and I’ll say it again again again they have underlining problem TAKE THEM TO THE VET VETERINARIAN HAVE THE VET, VETERINARIAN, TECHNICIAN, AND DOCTOR EXAMINE THE DOG TAKE SKIN GRAPHS WHATEVER THE BEST HAS TO DO. DON’T BLAME THE PRODUCT UNLESS YOU DID THAT AND IF YOU DID IT AND THEN DOCTOR RUNS TEXT AND SAID YES, IT WAS CAUSED BY THAT PRODUCT. WELL HENCE THERE YOU GO AND IT’S THE PRODUCT FAULT BUT A 99.999% IT’S NOT THE PRODUCT. Started having dogs when we first got married we have we had seven English mastiffs yeah it’s addicting and they had puppies and everything so anyways I’ve been using this on my dogs from year 2000 and I use them before that on my other dog so I’ve always used it really and I love it. I mean, I swear by it this stuff is great. My dogs do not get flea or I mean I have to put a spray on them to detail the mosquitoes, but don’t see my bugs biting them. It’s pricey, but it’s worth it. You don’t wanna have your dogs get Lyme disease or you know from ticks, I really suggest this. No bother my dog knock on wood you know in the other thing is I don’t use this year around. I only use it from spring until after fall. I don’t feel I really needed in the winter time. It’s too cold outside for anything to live so I’m up Northeast And I don’t seem to have any problem and they’re not using it as soon as spring hits that’s that boom they’re on it.
J**H
The GOOD and BAD.. Kills EVERYTHING
So this stuff kills and prevents it ALL! That's the good part! The bad is... it kills and prevents it all... SO if I continually put this on my dog... onto his skin.. down his back... and your skin is the largest organ that absorbs it... This cannot be good for my dog long term. I used to do this when flea/tick season was in high gear in my area (google flea/tick season for your state) and then stop in the winter months. Then I slowly just tapered off and stopped using this all together. It works and works well. My dog has no issue with it at all. The months I had put this on him, no flea or tick or mosquito in sight. It does spread into his long fur and takes a bit to dry/absorb like a day or two so that can be messy. You can't really pet him down his back at that time. You're not supposed to bathe them before or right after application. He never had any skin rashes or negative side effects from it. That being said, I personally decided to stop using it monthly. I don't take him to tick heavy areas like woods and if I do, I always, always, always do a thorough tick check on him. It's tedious, he has long, thick hair (golden retriever) but worth it 1000%. Of all the things in life I will mess around with, ticks and the diseases they carry (esp. lyme) are not one of them. Fleas, I will treat with capstar if need be but not really any fleas get on him. That being said I still purchase and keep this stuff around, WHY? because it kills everything. It's amazing to have on hand for emergencies, mainly like when a tick ATTACHES to him and I'm so scared if I pull it off wrong, it's head will still be in his skin (this is bad because it can still transmit diseases this way). SO when that happens, I get this out, put a generous DROP onto the tick and let it do it's magic. Let all those chemicals and pesticides and whatever kill that TICK at least paralyze it so it cannot bite and hold onto my dog's skin anymore. This takes, well I give it 30 seconds but usually a min or so to be safe. Then, I do what they say to do, grab the tick with tweezers and gently twist and off it comes head and all. I then, because I hate them so much (the only thing worse and scarier than spiders are ticks) burn them with a lighter. I show them NO mercy. Anyways, this product works, it doesn't have any bad effects on my dog, BUT I don't use it regularly anymore because I think it can be a lot on my dog's body/immune system. I DO keep it around though for emergencies that can and do crop up. That's part of life and owning a dog. So would I repurchase, YES, would I recommend? Yes. Just not all the time, but to have on hand. I'm not saying eliminate all chemicals and never use them, I just reduce WHEN I can.
Y**N
It works and works fantastically
I've been using K9 Advantix (I and II), and I've never had to worry about ticks, fleas or mosquitos, and I live out in the woods in a state that has these critters *everywhere*. My dogs walk all around in the fenced off area of ~4 acres, which I keep mowed to 3.5 inches and only a few trees in the main backyard but a .5 acre cedar grove in the front of the house. Cedar keeps the climbing bugs at bay well enough, but walking the fence line in the back and around the 100 yd x 50 yd pond and I have to check for ticks on me when I get in. The dogs will have a couple on them, but they never get the chance to dig in, so leaving them outside a lot of the day and night doesn't concern me. When they're inside, wherever they sit or lay, they're leaving an extremely small bit of this stuff on the material that also kills the crawling critters. The pond, naturally has mosquitos, but they don't hardly land on the dogs...unfortunately they DO land on me. As I said, I've used this stuff for decades on my dogs and because of it they're not uncomfortable from biting insects and the mosquitos pretty much leave them alone or die after lighting on them and don't infect them with heartworms. Also, this is like water, so when putting it on the dogs you need to put it in several spots on their back for it to work best. Because it's a water-type stuff, no more messy, gunky oil-based junk to get all over your hands or places they lie or collect dust/dirt/etc. Overall this can't be beat since it covers pretty much any critters that would love to make a home on your dog.
R**N
My go to for Flea and tick prevention.
After trying several different flea and tick treatments over the years, K9 Advantix has consistently been one of the most effective options for my dog. Application is quick and straightforward, and within a short time I noticed a significant reduction in fleas. Living in an area where ticks are common, it’s reassuring to know my dog has reliable protection during walks, hikes, and time spent outdoors. One thing I appreciate is that it doesn’t leave a heavy, greasy residue once it’s had time to dry, and my dog hasn’t shown any signs of irritation after application. Following the recommended dosing schedule has kept the protection consistent month after month. The peace of mind alone makes it worth the investment. Keeping fleas and ticks under control is much easier than dealing with an infestation, and this product has helped do exactly that. Based on my experience, K9 Advantix is a dependable choice for pet owners looking for effective, easy-to-use flea and tick protection.
T**L
Works to Keep My Home Flea Free
This is My go to for flea protection. My vet recommended these drops and since we haven’t had dogs, we have always used them, and I have never found a flea. After we put these on, we always have to make sure that we do not put their backs until it is nice and soaked in. Once it has soaked into their skin and we are able to give them a bath to get rid of the oily spot where we applied the medication. I have found these straps to be safe to use, I have never noticed any scratching or skin irritation. This product has protected my dogs, my yard and my house for over 5 years.
N**B
Advantix 2 losing its effectiveness?
Used Advantix 2 for several years on my 3 large dogs. Worked 90 percent of the time. They got ticks infrequently. and they were often dead. We live in a rural area with woods and fields left wild as well as farms. Then last year and this year i noticed the the big yellow Texas ticks were not dying and stayed on my dogs until i pulled them off. They remained alive until i disposed of them. Other ticks died on the dog or in the container i put hem in to see if they survived. My Vet wants me to switch to Simparica now after finding that they have Ehrlichia antibodies from infected ticks. Advantix@ must not be working on this generation of ticks.
Trustpilot
2 weeks ago
2 months ago